DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8093 and CG17097

DIOPT Version :9

Sequence 1:	NP_001286441.1	Gene:	CG8093 / 36686	FlyBaseID:	FBgn0033999	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_609429.1	Gene:	CG17097 / 34461	FlyBaseID:	FBgn0265264	Length:	1087	Species:	Drosophila melanogaster

Alignment Length:	372	Identity:	124/372 - (33%)
Similarity:	205/372 - (55%)	Gaps:	9/372 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 SSVTTVTIVRGHGYEIEEHEVQTSDGYILTMHRIPYSKNTGYDGPRPVVFLMHGLLCSSSDWVLA 91
            :.:|||.::..:||..|.:.|.:.|||.|.:||||      ..|..||: |:|||:.||:.||..
  Fly   722 TKLTTVDLIEKYGYPSETNYVTSEDGYRLCLHRIP------RPGAEPVL-LVHGLMASSASWVEL 779

  Fly    92 GPHSGLAYLLSEAGYDVWMGNARGNTYSKRHASKSPLLQPFWNFEWHDIGIYDLPAMMDYVLYWT 156
            ||..||||:|...||||||.|.|||.||:.:.::......:|:|.:|:||.:|:||.:|::|..|
  Fly   780 GPKDGLAYILYRKGYDVWMLNTRGNIYSRENLNRRLKPNKYWDFSFHEIGKFDVPAAIDHILIHT 844

  Fly   157 NVTQLTYVGHSQGTTSFFVLNSMIPRFKSRIRSAHLLAPVAWMEHMESPLATVGGPLLGQPNAFV 221
            :..::.|:|||||:|.|||:.|..|.:..::.....|:|..:::...||:....|...|:.:..:
  Fly   845 HKPKIQYIGHSQGSTVFFVMCSERPNYAHKVNLMQALSPTVYLQENRSPVLKFLGMFKGKYSMLL 909

  Fly   222 ELFGSAEFLPNTQLMNLFGALLCSDEAISQFMCTNTLFLLGGWNSPYINETLLPDIMATTPAGCS 286
            .|.|..|....|:|:..|...:||...:...:|....|:|.|::....|.||.|.:.|....|.|
  Fly   910 NLLGGYEISAKTKLIQQFRQHICSGSELGSSICAIFDFVLCGFDWKSFNTTLTPIVAAHASQGAS 974

  Fly   287 VNQIFHYLQEYNSGYFRQFDYGSTRNKKEYSSKTPPEYDVEGIDVPTYLYYSDNDYFASLIDVDR 351
            ..||:||.|......|::||:|:..|:..|.|..||.|::........|::.:.|:..|..||.|
  Fly   975 AKQIYHYAQLQGDLNFQRFDHGAVLNRVRYESSEPPAYNLSQTTSKVVLHHGEGDWLGSTSDVIR 1039

  Fly   352 LRYTMNPSALKSAYRMPEEKWNHIDFLWGLNIKEILYDRVINDINNA 398
            |:..: |:.::|. ::..|.::|.||....:::.:||..|:..::.:
  Fly  1040 LQERL-PNLVESR-KVNFEGFSHFDFTLSKDVRPLLYSHVLRHLSTS 1084

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8093	NP_001286441.1	PLN02872	9..392	CDD:215470	123/364 (34%)
		Abhydro_lipase	31..92	CDD:282003	25/60 (42%)
		Abhydrolase_5	74..>214	CDD:289465	56/139 (40%)
CG17097	NP_609429.1	Abhydro_lipase	726..780	CDD:282003	25/60 (42%)
		MhpC	746..1061	CDD:223669	111/323 (34%)
		Abhydrolase_5	762..>899	CDD:289465	56/137 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439481
Domainoid	1	1.000	150	1.000	Domainoid score	I1414
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		otm46497
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.850