DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8093 and Lipo1

DIOPT Version :9

Sequence 1:	NP_001286441.1	Gene:	CG8093 / 36686	FlyBaseID:	FBgn0033999	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	XP_006231364.1	Gene:	Lipo1 / 294097	RGDID:	1565682	Length:	397	Species:	Rattus norvegicus

Alignment Length:	370	Identity:	125/370 - (33%)
Similarity:	196/370 - (52%)	Gaps:	15/370 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 SSVTTVTIVRGHGYEIEEHEVQTSDGYILTMHRIPYSK-NTGYDGPRPVVFLMHGLLCSSSDWVL 90
            |.:....|::...|...|:||.|.|||||.::|||:.| |.....|:.|||..|||..:...||.
  Rat    29 SHMNVSEIIKYWNYPSLEYEVVTDDGYILPINRIPHGKNNANSSAPKMVVFCQHGLFSTPGVWVA 93

  Fly    91 AGPHSGLAYLLSEAGYDVWMGNARGNTYSKRHASKSPLLQPFWNFEWHDIGIYDLPAMMDYVLYW 155
            ..|.:.||::|:|||||||:||:||:|::|:|.:.||..:.||.|.:..:..|||||.::::|..
  Rat    94 NPPDNSLAFILAEAGYDVWLGNSRGSTWAKKHVTLSPDSEEFWAFSFDQMIAYDLPATINFILNT 158

  Fly   156 TNVTQLTYVGHSQGTTSFFVLNSMIPRFKSRIRSAHLLAPVAWMEHMESPLATVGGPLLG--QPN 218
            |...|:.|:|||.||.......|.......:|:...|:|||..:::::.     .|.||.  .|.
  Rat   159 TGQEQIYYIGHSLGTLIALGAFSTNQELAEKIKLNILIAPVRTVKYVKG-----FGRLLAYFSPE 218

  Fly   219 AFVELFGSAEFLPNTQLMNLFGALLCSDEAISQFMCTNTLFLLGGWNSPYINETLLPDIMATTPA 283
            ||..:||..|||| |.:.:.:...:|:.:.:.. .|...|..|.|::...:|.:.:...:..:.|
  Rat   219 AFKLVFGKKEFLP-TVVFSEYSKYVCNIKLVDA-GCAGVLGSLTGFSEDQLNTSRIDVYITHSLA 281

  Fly   284 GCSVNQIFHYLQEYNSGYFRQFDYGS-TRNKKEYSSKTPPEYDVEGIDVPTYLYYSDNDYFASLI 347
            |.|...:.|..|...||.|:.:|:|| :.|.:.|:..|||.|.||.:.|||.::....|:.|...
  Rat   282 GTSTQILIHAGQAIRSGEFQAYDWGSPSLNMQHYNQTTPPLYSVENMKVPTVMFTGLKDFLADPK 346

  Fly   348 DVDRLRYTMNPSALKSAYRMPEEKWNHIDFLWGLNIKEILYDRVI 392
            ||..|    .|......|.....:::|:||:.|||.|..:.|.::
  Rat   347 DVANL----VPKIFNLIYHKTIPEFSHLDFIVGLNAKTEVSDEIL 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8093	NP_001286441.1	PLN02872	9..392	CDD:215470	125/368 (34%)
		Abhydro_lipase	31..92	CDD:282003	25/61 (41%)
		Abhydrolase_5	74..>214	CDD:289465	52/139 (37%)
Lipo1	XP_006231364.1	Abhydro_lipase	33..94	CDD:282003	25/60 (42%)
		Abhydrolase_1	77..375	CDD:278959	102/308 (33%)
		Abhydrolase_5	77..>199	CDD:289465	49/121 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335468
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2916
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm8975
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.810