DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8093 and SPBC16A3.12c

DIOPT Version :9

Sequence 1:	NP_001286441.1	Gene:	CG8093 / 36686	FlyBaseID:	FBgn0033999	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_596777.1	Gene:	SPBC16A3.12c / 2539875	PomBaseID:	SPBC16A3.12c	Length:	443	Species:	Schizosaccharomyces pombe

Alignment Length:	379	Identity:	110/379 - (29%)
Similarity:	177/379 - (46%)	Gaps:	44/379 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 IVRGHGYEIEEHEVQTSDGYILTMHRIPYSKNTGYDGPRPVVFLMHGLLCSSSDWVLAG-PHSGL 97
            |....||.:|||.|:|.|.:||.:|||.:.|.:.:  .|.||:..|||:.:|..||... ....|
pombe    78 ICEAFGYRVEEHLVRTQDNFILCLHRITHPKQSQH--KREVVYCHHGLMTNSELWVAVNESERSL 140

  Fly    98 AYLLSEAGYDVWMGNARGNTYSKRHASKSPLLQPFWNFEWHDIGIYDLPAMMDYVLYWTNVTQLT 162
            .::|.|:|||||:||.|||.||::|.:..|..:.||||...|:.::|:|..:||:|..|...:|.
pombe   141 PFVLIESGYDVWLGNNRGNKYSRKHITYKPKDEEFWNFSLDDMAMFDIPDTVDYILRETGREKLN 205

  Fly   163 YVGHSQGTTSFFVLNSMIPRFKSRIR----SAHLLAPVAWMEHMESPLATVGGPLLGQPNAFVEL 223
            |:|.||||.......|:.|....::.    .|...||..:..:....:..|      .|.....|
pombe   206 YIGFSQGTAQAMAALSINPDLNDKVNIFIGLAPAYAPKGFSNYFVDYIVKV------NPKIMYHL 264

  Fly   224 FGSAEFLPNTQLMNLFGALLCSDEAISQFMCTNTLFLLGGWNSPYI--NETLLPDIMATTPAGCS 286
            ||....||:.    .|...:|......:.:.. :|.:|..|:...|  |:.|..  .|...:..|
pombe   265 FGRRCLLPSV----TFWQNICYPPIFVKIVDV-SLKILFNWDLSNISLNQKLCG--YAHLYSFSS 322

  Fly   287 VNQIFHYLQEYNSGYFRQFD--------YGSTRNKKEYSSKTPPEYDVEGIDVPTYLYYSDNDYF 343
            |..:.|:||...:..|:.:|        |||    :.|.   .|.:....|..|..:.:...|
pombe   323 VKSVVHWLQIIKNCTFQLYDDDMALLAGYGS----RHYQ---VPLFPTNNIKCPMLILWGGKD-- 378

  Fly   344 ASLIDVDRLRYTMNPSALKSAYRMPEEKWNHIDFLWGLNIKEILYDRVINDINN 397
             :||:::.:|..:.|.|.:.:.    ..:.|:|||||.::||.::..||:.:.:
pombe   379 -TLINMEVMRTALPPHAKEVSI----AHYEHLDFLWGQDVKEEVFPVVIDALKH 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8093	NP_001286441.1	PLN02872	9..392	CDD:215470	108/372 (29%)
		Abhydro_lipase	31..92	CDD:282003	24/57 (42%)
		Abhydrolase_5	74..>214	CDD:289465	49/144 (34%)
SPBC16A3.12c	NP_596777.1	Abhydro_lipase	75..131	CDD:282003	22/54 (41%)
		Abhydrolase_1	116..410	CDD:278959	88/320 (28%)
		Abhydrolase	<171..>242	CDD:304388	21/70 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	133	1.000	Domainoid score	I1290
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1188
OMA	1	1.010	-	-		QHG55134
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm9260
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1506
SonicParanoid	1	1.000	-	-		X80
TreeFam	0	0.000	Not matched by this tool.
	11	10.800