DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8093 and SPBC14C8.15

DIOPT Version :9

Sequence 1:	NP_001286441.1	Gene:	CG8093 / 36686	FlyBaseID:	FBgn0033999	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_595918.1	Gene:	SPBC14C8.15 / 2539842	PomBaseID:	SPBC14C8.15	Length:	460	Species:	Schizosaccharomyces pombe

Alignment Length:	391	Identity:	108/391 - (27%)
Similarity:	177/391 - (45%)	Gaps:	58/391 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 TVTIVRGHGYEIEEHEVQTSDGYILTMHRIPYSKNTG------YDGPRPVVFLMHGLLCSSSDWV 89
            |:.:...|||::|||.|:|:|||:|.:||: |.|..|      |   .|.|..:|||:.:|..||
pombe    75 TIDLCALHGYDLEEHFVRTTDGYLLGLHRV-YKKKKGKIEELNY---LPPVLFIHGLMMNSESWV 135

  Fly    90 L-AGPHSGLAYLLSEAGYDVWMGNARGNTYSKRHASKSPLLQPFWNFEWHDIGIYDLPAMMDYVL 153
            . ......:.:.|.|.|||||:||.|||.||.::...|.....||:|....|.|:|:|:::.|:|
pombe   136 CNLKKEDAIPFALVEQGYDVWLGNLRGNKYSIKNIKFSSQNPKFWDFSLDSIAIFDIPSIVKYIL 200

  Fly   154 YWTNVTQLTYVGHSQGTTSFFVLNSMIPRFKSRIRSAHLLAP-----------VAWMEHMESPLA 207
            ...:...::.||.|||....|...|:....::.:|:...|||           |..:.|..|.|.
pombe   201 SVNSFDSISLVGFSQGAILAFAALSIDTELRNSVRAFIALAPAIAPKKYSGRTVKSIIHANSQLL 265

  Fly   208 TVGGPLLGQPNAFVELFGSAEFLPNTQLMNLFGALLCSDEAISQFMCTNTLFLLGGWNSPYINET 272
            .:   :.|:.:    :.|||.|........:|..:      :..|:   ..||  .|....|:||
pombe   266 YL---MFGRNS----MLGSAVFWQAVLYPPVFAKI------VDLFL---RFFL--SWTGKNISET 312

  Fly   273 ----LLPDIMATTPAGCSVNQIFHYLQEYNSGYFRQFDYGSTRNKKEYSSKTP--PEYDVEGIDV 331
                ....:.:.|...|.|    |:.|.......:.:| .|...|..|.:...  ..|.:|.|.:
pombe   313 QKIVAYSHLYSFTSVKCFV----HWAQITRRKVLQMYD-DSPGFKPSYYTNLNRIARYPIENIRL 372

  Fly   332 PTYLYYSDNDYFASLIDVDRLRYTMNPSALKSAYRMPEEKWNHIDFLWGLNIKEILYDRVINDIN 396
            |..|.|..||   :::|::.|:..:.|  |....::|  .:.|:|.:.|...|:|:..:|:..:|
pombe   373 PITLVYGSND---NMVDIETLKTQLPP--LSQCIQIP--NYEHLDIIMGDTKKDIVIQQVVEQLN 430

  Fly   397 N 397
            :
pombe   431 H 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8093	NP_001286441.1	PLN02872	9..392	CDD:215470	106/384 (28%)
		Abhydro_lipase	31..92	CDD:282003	27/67 (40%)
		Abhydrolase_5	74..>214	CDD:289465	46/151 (30%)
SPBC14C8.15	NP_595918.1	Abhydro_lipase	75..138	CDD:282003	27/66 (41%)
		Abhydrolase_1	119..412	CDD:278959	84/322 (26%)
		Abhydrolase_5	120..>260	CDD:289465	43/139 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	133	1.000	Domainoid score	I1290
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1188
OMA	1	1.010	-	-		QHG55134
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm9260
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
TreeFam	0	0.000	Not matched by this tool.
	10	9.770