DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8093 and LOC100360690

DIOPT Version :9

Sequence 1:	NP_001286441.1	Gene:	CG8093 / 36686	FlyBaseID:	FBgn0033999	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	XP_006231366.1	Gene:	LOC100360690 / 100360690	RGDID:	2321667	Length:	399	Species:	Rattus norvegicus

Alignment Length:	398	Identity:	130/398 - (32%)
Similarity:	208/398 - (52%)	Gaps:	20/398 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 VVQLIAVFLSLGLANALPADTGRASSVTTVTIVRGHGYEIEEHEVQTSDGYILTMHRIPYSKN-- 65
            |:..|..||     ||.|.:.  .:::....|:...|||.|||||.|.|||||.:.|||:.||
  Rat    13 VIGSIFCFL-----NAKPKNP--EANMNVSQIISYWGYESEEHEVMTEDGYILLIFRIPHGKNEN 70

  Fly    66 -TGYDGPRPVVFLMHGLLCSSSDWVLAGPHSGLAYLLSEAGYDVWMGNARGNTYSKRHASKSPLL 129
             :.::..||||:|.|||..|:..|:|..|.:.||:||::||::||:||:||...:::|....|..
  Rat    71 KSSHNTRRPVVYLHHGLTVSADYWILDPPSNCLAFLLADAGFEVWLGNSRGTNNARKHVRLDPDS 135

  Fly   130 QPFWNFEWHDIGIYDLPAMMDYVLYWTNVTQLTYVGHSQGTTSFFVLNSMIPRFKSRIRSAHLLA 194
            :.||:|.:::...|||||::.::|..|..||:.|:|||||....:...:..|:...:|:....|.
  Rat   136 KEFWDFSFNEQIEYDLPAIIYFILNETRQTQIYYIGHSQGVYLAYAAFATNPQLAQKIKINFALG 200

  Fly   195 PVAWMEHMESPLATVGGPLLGQPNAFVELFGSAEFLPNTQLMNLFGALLCSDEAISQFMCTNTLF 259
            ||...:::.....|:.   ...|.....:||..:....:...::. ..||..|.|:. .||:.|.
  Rat   201 PVVITKYLTGVFRTIA---YIHPTVIKTMFGEKDIFSKSNANDIL-RFLCHREQIAT-ACTSLLI 260

  Fly   260 LLGGWNSPYINETLLPDIMATTPAGCSVNQIFHYLQEYNSGYFRQFDYGS-TRNKKEYSSKTPPE 323
            :|.|:|...:||:.:.......|||.||..|.|:.|...||.|:.:|:|| :.|...|:..|||.
  Rat   261 VLFGYNPGNLNESRIDVYSEHIPAGTSVRSILHFSQGIRSGLFQAYDWGSESLNVLHYNQSTPPI 325

  Fly   324 YDVEGIDVPTYLYYSDNDYFASLIDVDRLRYTMNPSALKSAYRMPEEKWNHIDFLWGLNIKEILY 388
            |::|.:.|.|.::..:.|......||..|. ...|:.:   |......:||:||:.|.:....:|
  Rat   326 YNIEDMKVRTAMWSGERDLLGDPKDVKNLA-AKTPNLI---YHKKIPHYNHMDFILGKDAVVQVY 386

  Fly   389 DRVINDIN 396
            .::|..||
  Rat   387 RKIIEFIN 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8093	NP_001286441.1	PLN02872	9..392	CDD:215470	125/386 (32%)
		Abhydro_lipase	31..92	CDD:282003	31/63 (49%)
		Abhydrolase_5	74..>214	CDD:289465	48/139 (35%)
LOC100360690	XP_006231366.1	Abhydro_lipase	34..96	CDD:282003	30/61 (49%)
		Abhydrolase_1	79..378	CDD:278959	97/307 (32%)
		Abhydrolase_5	79..245	CDD:289465	52/169 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335469
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2916
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm8975
orthoMCL	1	0.900	-	-		OOG6_100408
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.910