DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment row and Zfp280b

DIOPT Version :9

Sequence 1:NP_001260992.1 Gene:row / 36685 FlyBaseID:FBgn0033998 Length:1301 Species:Drosophila melanogaster
Sequence 2:NP_803426.2 Gene:Zfp280b / 64453 MGIID:1927865 Length:534 Species:Mus musculus


Alignment Length:472 Identity:115/472 - (24%)
Similarity:167/472 - (35%) Gaps:124/472 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   540 TYALQAFN-NIIIHIAEQTRVTTNE-----TITQRLYQVATNPFKDWS----ILPANYKETPANA 594
            |.|.|..| ||:..:...:|:....     |.||||.  .:.|....|    :|||:..|:.:..
Mouse    58 TSASQPANSNILNRVTPGSRLKRKHDRLRATTTQRLQ--PSRPAAPTSEAVVVLPASPAESRSTD 120

  Fly   595 APKRLKKPINDADYVVSNKIPKKEKDRDIASSGVKRGRPPNALGTPPPQLPIKK----------- 648
            :|..: :|::::||       :....:.:.||..|...|...|.: ....|:|.           
Mouse   121 SPIAI-EPLSESDY-------RSSSPQVVPSSSSKCCSPLVTLSS-SENSPVKAALSGGDLNENL 176

  Fly   649 ---------GPGR---------------PPGSTNQTKGDRATTSS---SKSLSKSLIAKGLGKKP 686
                     .|.|               ||..|..|...:..|.|   ..|||:  :..|   .|
Mouse   177 YVSKCHFSINPQRPDHSIEIVEPLSSALPPSGTFHTSNMQQRTPSFDAPNSLSR--LVNG---AP 236

  Fly   687 KEKDEKIPM-------------VIKKEEDDLRG-----LEELYYG--ISDGTDEYHEIFPYSTPR 731
            ..:|...|.             ..::..|..:|     |.:.|||  ..||..|          :
Mouse   237 PSEDSAHPRQDSGLAEADFSSPASQETFDPKKGSLTLLLSDFYYGQYKGDGKPE----------Q 291

  Fly   732 TVHNELAKTVECPICLNGDSFDSNEKLQTHLVSHISPE--GKQHQFQ----CLFCLEKHPTESVL 790
            ..|.    |.:||.||..   ..|.|...|...|:..|  |.:..::    ||.|..:..:...|
Mouse   292 KTHT----TFKCPSCLKA---LKNVKFMNHTKHHLELERQGSEDAWESHTTCLRCHRQFDSPFQL 349

  Fly   791 AKHNQIMHPTETKTEGSPSYYCLICQQRHNSLHLLTAHLQKVHSTLELPYWCHSCGYRSSSHRDL 855
            ..|...:|     |...||..|.||:....:..:|..|::..|...|:||.|..|.||||...|:
Mouse   350 ECHIDRVH-----TSPDPSVVCKICELSFETDQVLLQHMKDNHKPGEMPYVCQVCKYRSSGFADV 409

  Fly   856 VRHFYDDHKHQNFLQCPYCLDIFYFSKLGVVNQLRIEHYFMHLDEHINKRDPSLRCQKCSLSFLE 920
            ..||...|.:...|.||:||.||   |.|:       .|..|...|..:  ...:|.||.|.||.
Mouse   410 ETHFTKCHVNTKNLLCPFCLKIF---KTGM-------PYMCHYRGHWER--SGHQCSKCRLQFLT 462

  Fly   921 KGDLKQHAVQHHVSMTK 937
            ..:..:|..|.|....|
Mouse   463 FKEKMEHKTQCHQMFKK 479

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rowNP_001260992.1 C2H2 Zn finger 777..798 CDD:275368 5/20 (25%)
C2H2 Zn finger 812..833 CDD:275368 5/20 (25%)
C2H2 Zn finger 842..858 CDD:275368 7/15 (47%)
Zfp280bNP_803426.2 DUF4195 53..221 CDD:404681 36/173 (21%)
C2H2 Zn finger 336..357 CDD:275368 5/20 (25%)
C2H2 Zn finger 366..387 CDD:275368 5/20 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - otm43222
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
32.870

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