DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment row and zbtb12.1

DIOPT Version :9

Sequence 1:NP_001260992.1 Gene:row / 36685 FlyBaseID:FBgn0033998 Length:1301 Species:Drosophila melanogaster
Sequence 2:NP_001038352.1 Gene:zbtb12.1 / 559143 ZFINID:ZDB-GENE-060503-875 Length:483 Species:Danio rerio


Alignment Length:425 Identity:86/425 - (20%)
Similarity:126/425 - (29%) Gaps:161/425 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly   688 EKDEKIPMVIKKEEDDLRGLEELYYGISDGTDEYHEIF--PYSTPRTVHNELAKTVECPIC---- 746
            :..|.:|:::.....|...|.|...|.  |:|.|..|.  |..|| ....|..:|....:|    
Zfish   147 DDSESMPVIVSVRGSDSSSLFETEDGY--GSDVYQVIIDEPEKTP-DAEEENRETASEDLCQLDM 208

  Fly   747 ---------------LNGDSFDSNEKLQTHLVSHISPEGKQHQ--------------FQCLFCLE 782
                           |:|:...|..|       .|...|.:.:              :|..:|.:
Zfish   209 GIEEPNMEVQAKYDDLHGEQQYSERK-------GIKGRGLKRRKRYVFKKDRTSLGNYQDNWCFQ 266

  Fly   783 KHPTESVLAK----------HNQ-----IMHPTETKTE----------GSPSYYCLICQQRHNSL 822
              ..|.::.|          .||     .:| ||.|.|          |.|:::.:........|
Zfish   267 --TAEEIMGKSETDFQADYQSNQRLTDCSVH-TEYKNEGGPGEDIGSDGGPAHFRIEASSGEEEL 328

  Fly   823 HLLTAHLQK-------VHSTLEL--PYWCHSCGYRSSSHRDLVRHFYDDHKHQNFLQCPYCLDIF 878
            .:.|...::       |.||..:  |..|..||...||.:||..|...  .||.:: ||.|...|
Zfish   329 GIGTPSNERGATDESVVGSTSNVTGPVVCEQCGLAFSSTQDLAMHSLS--AHQQYI-CPCCRKQF 390

  Fly   879 YFSKLGVVNQLRIEHYFMHLDEHINKRDPSLRCQKCSLSFLEKGDLKQHAVQHHVSMTKTNRPVR 943
            ..|:    |..|  |..:|.|   |.|.||  |..|..:|.:|..:..|                
Zfish   391 SNSR----NLNR--HMLLHRD---NSRLPS--CPLCHKTFTQKSTMYDH---------------- 428

  Fly   944 LLLNNSMLIPPPKIRTHHREQPPFSTYKRPVFFAFLEGKTCAECNTDFASEETHYTGWLHCVKCN 1008
                         :..|..|:|                ..||.|...||...             
Zfish   429 -------------MNVHSGERP----------------YVCAYCPISFAHRS------------- 451

  Fly  1009 YQTCCERAQFRHGVECNGNFVDAMEVNMPQEMHCI 1043
                   |..||.:|.:|..:......|.:..|.|
Zfish   452 -------ALRRHLLEQHGKTMPQNHQEMQRNKHSI 479

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rowNP_001260992.1 C2H2 Zn finger 777..798 CDD:275368 5/35 (14%)
C2H2 Zn finger 812..833 CDD:275368 2/27 (7%)
C2H2 Zn finger 842..858 CDD:275368 7/15 (47%)
zbtb12.1NP_001038352.1 BTB 21..122 CDD:279045
BTB 32..125 CDD:197585
C2H2 Zn finger 357..378 CDD:275368 8/22 (36%)
C2H2 Zn finger 383..403 CDD:275368 8/25 (32%)
C2H2 Zn finger 412..432 CDD:275368 5/48 (10%)
zf-H2C2_2 428..449 CDD:290200 8/65 (12%)
C2H2 Zn finger 440..457 CDD:275368 7/36 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24408
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.100

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