Protein Alignment row and Plagl2

DIOPT Version :10

• Sequence 1: NP_001260992.1
• Gene: row / 36685
• FlyBaseID: FBgn0033998
• Length: 1301
• Species: Drosophila melanogaster
• Sequence 2: NP_061277.2
• Gene: Plagl2 / 54711
• MGIID: 1933165
• Length: 496
• Species: Mus musculus
• Alignment Length: 547
• Identity: 108/547 - (19%)
• Similarity: 175/547 - (31%)
• Gaps: 143/547 - (26%)

  Fly   714 ISDGTDEYHEIFPYSTPRTVHNELAKTVECPICLNGDSFDSNEKLQTHLVSHISPEGKQHQFQCL 778
            |.|...| .|:.....||....|....|:|...::|..|.:.|||:.|.:.|  ||.:.:.
Mouse    12 IQDAKQE-EEVGWKLVPRPRGREAESQVKCQCEISGTPFSNGEKLRPHSLPH--PEQRPYS---- 69

  Fly   779 FCLEKHPTESVLAKHNQIMHPTETKTEGSPSYYCLICQQRHNSLHLLTAHLQKVHSTLELPYWCH 843
             |.:.|..::..:|:....| ..|.:...| :.|:.|.:..:....|..||| .|...:....|.
Mouse    70 -CPQLHCGKAFASKYKLYRH-MATHSAQKP-HQCMYCDKMFHRKDHLRNHLQ-THDPNKEALHCS 130

  Fly   844 SCGYRSSSHRDLVRHFYDDHKHQNFLQCPYCLDIFYFSKLGVVNQLRIEHYFMHLDEHI-----N 903
            .||...::.....||..........|.|..||..|..:      |..:||...| ...:     .
Mouse   131 ECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFEST------QALLEHLKAH-SRRVAGGAKE 188

  Fly   904 KRDPSLRCQKCSLSFLEKGDLKQHAVQHHVSMTKTNRPVRLLLNNSMLIPPPKIRTHHREQPPFS 968
            |:.|   |..|...|..:.|:::|.|.|      |.|.
Mouse   189 KKHP---CDHCDRRFYTRKDVRRHLVVH------TGRK--------------------------- 217

  Fly   969 TYKRPVFFAFLEGKTCAECNTDFASEETHYTGWLHCVKCNYQTCCERAQFRHGVECNGNFVDAME 1033
                    .||    |..|...|..:: |.|  .|..|.:.|                   :.::
Mouse   218 --------DFL----CQYCAQRFGRKD-HLT--RHVKKSHSQ-------------------ELLK 248

  Fly  1034 VNM-PQEMHCICGFATGNGNKMAQHLANCGLSTCYPSLEAASENAVKRNMLDMLGLVRRD--GET 1095
            :.. |.:|                    .||.:|      :|..:||..:..:|.:..||  |..
Mouse   249 IKTEPVDM--------------------LGLLSC------SSTVSVKEELSPVLCMASRDVMGAK 287

  Fly  1096 SGEG-ADISETADDVADQSSDMLPPQEDHHLQQHHQQVGHQQQMQGQPNEPQAELQQEYLSAPVE 1159
            :..| ..:......:....|..:|    |.|..:...:|....::..|....|:|..:|......
Mouse   288 AFPGMLPMGMYGAHIPTMPSAGMP----HSLVHNTLPMGMSYPLESSPISSSAQLPPKYQLGSTS 348

  Fly  1160 HEPVQNMPVH-QSMPVQQTGPIQFGEMEAAPVLLDTQQQVQPTPDYAQVSVVQQHQQQQPYGLSN 1223
            :.|.:...|. .|...:..|.:.....|..|        ..|.|..|...:.:....:.|   :|
Mouse   349 YLPDKLPKVEVDSFLAELPGSLSLSSAEPQP--------ASPQPAAAAALLDEALLAKSP---AN 402

  Fly  1224 YGQSSLATDIDMP-LIGELSEP-NAPP 1248
            ..::..|.::|.. |:|.|  | |.||
Mouse   403 LSEALCAANVDFSHLLGFL--PLNLPP 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
row	NP_001260992.1	C2H2 Zn finger	777..798	CDD:275368	3/20 (15%)
		C2H2 Zn finger	812..833	CDD:275368	6/20 (30%)
		C2H2 Zn finger	842..858	CDD:275368	3/15 (20%)
Plagl2	NP_061277.2	C2H2 Zn finger	42..62	CDD:275368	6/19 (32%)
		C2H2 Zn finger	70..92	CDD:275368	4/22 (18%)
		zf-H2C2_2	85..107	CDD:463886	5/23 (22%)
		zf-C2H2	98..120	CDD:395048	6/22 (27%)
		C2H2 Zn finger	100..120	CDD:275368	6/20 (30%)
		C2H2 Zn finger	129..149	CDD:275368	5/19 (26%)
		C2H2 Zn finger	158..178	CDD:275368	7/25 (28%)
		C2H2 Zn finger	193..213	CDD:275368	6/19 (32%)
		C2H2 Zn finger	221..239	CDD:275368	6/20 (30%)