DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment row and CG1233

DIOPT Version :9

Sequence 1:	NP_001260992.1	Gene:	row / 36685	FlyBaseID:	FBgn0033998	Length:	1301	Species:	Drosophila melanogaster
Sequence 2:	NP_612034.1	Gene:	CG1233 / 38063	FlyBaseID:	FBgn0035137	Length:	1129	Species:	Drosophila melanogaster

Alignment Length:	664	Identity:	129/664 - (19%)
Similarity:	207/664 - (31%)	Gaps:	240/664 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   436 PITDGDRNYKKRFQAILEPLSRWVHKDSTICIDLTVDKITLFSMGFKNIVQAAATDNTAKHNNSA 500
            |||...:.:.|....:..|....:|.       .|||::.|.                    |..
  Fly   525 PITTKQKIFIKNVDILKAPQRGTLHL-------RTVDELNLM--------------------NRT 562

  Fly   501 VMEYLRRIVPRMFQNTLSLLSRQMIQQFLDELVWRESFGTYALQAFNNIIIHIAEQTRVTTNETI 565
            .:|:|  |||.:....::::....:||...|                     :..|.:..| ||:
  Fly   563 EVEHL--IVPNLEPMAMTMMELPPVQQQPME---------------------VTSQLKGPT-ETL 603

  Fly   566 TQRLYQVATN-PFKDWSILPANYK----------------ETP---ANAAP-KRLKKPINDADYV 609
            .:....::.: |.:|...||.:.:                .||   |||.| ..|..  |..|.:
  Fly   604 GEFQPSISESWPSEDGYDLPEDLECWPWMEDAVPEAGLVLPTPSEVANAPPLDGLSH--NAVDLL 666

  Fly   610 V---SNKIPKKEKDRDIASSGVKRGRPPNALGTPPPQLPIKKGPGRPPGSTNQTKGDRATTSSSK 671
            |   |:......:|...|..|...|    ..||.||.:|:....|              |.|.::
  Fly   667 VKDFSHLYAAPPEDTQNAEEGTAAG----GRGTVPPLVPVTSSEG--------------TASVAQ 713

  Fly   672 SLSKSLIAKGLGKKPKEKDEKIPMVIKKEEDDLRGLEE---LY---------------------- 711
            |.:       ||..|      :|.::....:....:|:   :|
  Fly   714 SAA-------LGSLP------VPPLVPLAAEMNAAIEKPARIYVANNLLPAAVDPPLLGGGTSVR 765

  Fly   712 ---YG------------ISDGTDEYHE---------IFPYSTPRTV------HN---ELAKTVEC 743
               ||            :|.|.::..|         :|.:.:|.|:      ||   ...:.|.|
  Fly   766 GRPYGAKHSGGAASKRKLSLGPNQVPEGGKCLVEGCMFRFKSPVTLEYHGRCHNGSLSSNQPVVC 830

  Fly   744 PICLNGDSFDSNEKLQTHLVSHISPEGKQHQ-----FQCLFCLEKHPTESVLAKHNQIMHPTETK 803
            |.| ...:|.:...|.|||       .:.||     :.|..|..|.|..|.|...:..:|..|.
  Fly   831 PEC-KSSNFSNWNCLHTHL-------WRTHQIDMELYSCQLCSFKTPIYSRLVNTHAKIHSEER- 886

  Fly   804 TEGSPSYYCLICQQRHNSLHLLTAHLQKVHSTLEL--------------------PYWCHSCGYR 848
                 :|.|..|.:...:...|..| :::|.|..|                    .:.|..||..
  Fly   887 -----NYKCEQCGKGFKNTKQLKNH-RRLHRTQGLGMGKQSNEQISVGPEGNPVVMHRCEDCGAA 945

  Fly   849 SSSHRDLVRHFYDDHKHQNFLQCPYCLDIFYFSKLGVVNQLRIEHYFMHLDEHINKRDPSLRCQK 913
            ....:.|..|...:...|  |:||.|.     .:.|..:.||     :||..|  :.....||..
  Fly   946 FKQKKTLREHLCKERNEQ--LECPECQ-----RRFGSKSSLR-----LHLRSH--QEHKRFRCDT 996

  Fly   914 CSLSFLEKGDLKQHAVQHHVSMTKT--NRPVRLLLNNSMLIPPPKIRTHHREQPPFST--YKRPV 974
            |.....:....::|...|..|...:  :...|.:.:.:..|   .::|.|.|| ..||  ||
  Fly   997 CDHETSDHNAYRRHLATHKESKRYSCPHCDFRAIQSTAFRI---HLQTRHPEQ-ELSTIIYK--- 1054

  Fly   975 FFAFLEGKTCAECN 988
                     |.:||
  Fly  1055 ---------CNQCN 1059

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
row	NP_001260992.1	C2H2 Zn finger	777..798	CDD:275368	6/20 (30%)
		C2H2 Zn finger	812..833	CDD:275368	4/20 (20%)
		C2H2 Zn finger	842..858	CDD:275368	4/15 (27%)
CG1233	NP_612034.1	C2H2 Zn finger	830..852	CDD:275368	8/29 (28%)
		C2H2 Zn finger	861..882	CDD:275368	6/20 (30%)
		zf-H2C2_2	875..899	CDD:290200	5/29 (17%)
		zf-C2H2	888..910	CDD:278523	5/22 (23%)
		C2H2 Zn finger	890..910	CDD:275368	4/20 (20%)
		zf-C2H2_2	893..999	CDD:289522	25/120 (21%)
		C2H2 Zn finger	939..956	CDD:275368	4/16 (25%)
		RPB9	966..1061	CDD:224510	28/122 (23%)
		C2H2 Zn finger	966..986	CDD:275368	8/29 (28%)
		C2H2 Zn finger	994..1014	CDD:275368	3/19 (16%)
		C2H2 Zn finger	1022..1042	CDD:275368	2/22 (9%)
		C2H2 Zn finger	1055..1075	CDD:275368	3/5 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24408
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100