DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment row and Zfp451

DIOPT Version :9

Sequence 1:	NP_001260992.1	Gene:	row / 36685	FlyBaseID:	FBgn0033998	Length:	1301	Species:	Drosophila melanogaster
Sequence 2:	NP_001028877.2	Gene:	Zfp451 / 316312	RGDID:	1305865	Length:	1052	Species:	Rattus norvegicus

Alignment Length:	553	Identity:	101/553 - (18%)
Similarity:	174/553 - (31%)	Gaps:	211/553 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   658 NQTKGDRATTSSSKSLSKSLIAKGLGKKPKEKDEKIPMVIKKEEDDLRGLEELYYGISDGTDEYH 722
            ||...|.|:|.|.|:                ...|:......||..|     ||..||:|:....
  Rat   368 NQVFMDEASTQSHKN----------------PGHKMSFANSVEESVL-----LYCHISEGSRPPC 411

  Fly   723 EIFPYSTP------RTVHNELAKTVEC-----PICLNGDSFDSNEKLQTHLVSHISPEGKQHQFQ 776
            ::..::.|      |.:.::.:...:|     .:.|..||.....::|.          ::....
  Rat   412 DLHLFNQPKISSLKRILSSKESSAEDCVIPTKKVNLGVDSQGGTARVQR----------QRSTVT 466

  Fly   777 CLF--CLEKHPTESVLAKHNQIMHPTETKTEGSPSYYCLICQQRHNSLHLLTAHLQKVHSTLELP 839
            ..|  |..:.|:|..:.||        ..:..:..|.|::|.:......::..|:.:.|....|.
  Rat   467 AWFCECSRRFPSEDAVEKH--------VFSANTMCYKCVVCGKVCEDSGVMRLHMSRFHGGAHLN 523

  Fly   840 ---YWCHSCGYRSSSHRDLVR---------HFYDDHKHQNFLQCPYCLDIFYFSKLGVVNQLRIE 892
               :||..|      .::|:|         .|:..|:
  Rat   524 NFLFWCRMC------KKELIRKDAIMAHVTEFHSGHR---------------------------- 554

  Fly   893 HYFMHLDEHINKRDPSLRCQKCSLSFLEKGDLKQHAVQHHVSMTKTNRPVRLLLNNSMLIPPPKI 957
             ||..:|| :....||                  .:.::|::..|...|: .::::|....||:.
  Rat   555 -YFYEMDE-VEAAVPS------------------SSTENHLNADKPPSPI-AVVDHSPASSPPRG 598

  Fly   958 R-----------------------THHREQPPFSTYKRPVFFAFLEGKTCAECNTDFASEETHYT 999
            |                       |.||    |..|            :||.|...|...||...
  Rat   599 RWQCRICEDMFDSHECVQQHCASLTSHR----FHRY------------SCAHCRKTFHKVETLCR 647

  Fly  1000 GWLHC-------VKCNYQTCC---------ERAQFRHGVE-CNGNFVDAMEVNMPQEMHCICGFA 1047
               ||       |:..|  ||         |.|...|..| .:|::|...|...       ....
  Rat   648 ---HCQDEHSGEVRMMY--CCGLCDLIFNKEEAFLSHYTEQHSGDYVFVPEKTK-------TSIK 700

  Fly  1048 TGNGNKMAQ--HLANCGLSTCYPSLEAASENAVKRNMLD----MLGLVRRDGETSGEGADISETA 1106
            |.:..|:.:  :|.:||   |:.|.      ..|.|..|    .|.::...|:........|.||
  Rat   701 TEDDFKIIETSNLLSCG---CHESY------ICKVNRRDDYDRCLQIMLEKGKLWFRCGSCSATA 756

  Fly  1107 DDVADQSSDMLPPQEDHHLQQHHQQVGHQQQMQ 1139
            .::||.::         |:.|.|::|...::.|
  Rat   757 QNLADINT---------HVCQAHRKVRGDEEQQ 780

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
row	NP_001260992.1	C2H2 Zn finger	777..798	CDD:275368	6/22 (27%)
		C2H2 Zn finger	812..833	CDD:275368	3/20 (15%)
		C2H2 Zn finger	842..858	CDD:275368	4/24 (17%)
Zfp451	NP_001028877.2	zf-Di19	630..685	CDD:398954	17/71 (24%)
Zfp451	NP_001028877.2	PIN_11	876..993	CDD:408272
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24408
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100