DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment row and Zfp280c

DIOPT Version :9

Sequence 1:	NP_001260992.1	Gene:	row / 36685	FlyBaseID:	FBgn0033998	Length:	1301	Species:	Drosophila melanogaster
Sequence 2:	XP_006257603.1	Gene:	Zfp280c / 302812	RGDID:	1564669	Length:	753	Species:	Rattus norvegicus

Alignment Length:	669	Identity:	135/669 - (20%)
Similarity:	227/669 - (33%)	Gaps:	222/669 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   563 ETITQRLYQVATNPFKDWSILPANY----KETP-ANAAPK--------RLKKPINDADYVVSNKI 614
            :|:::..: :.|:|..|.....|:.    |:.| :|...|        |||.|.:..   |::..
  Rat   137 QTVSKPTF-LKTSPQDDSGASSASLLDSTKDIPSSNVLQKSTGVNQTLRLKHPSSSK---VNSVN 197

  Fly   615 PKKEK-DRDIASSGVKRGRPPNALGTPPPQL------------PIKKGPGRP------------- 653
            |||.| :..|:.:|  || ..::|...|.:.            .|:...|:|
  Rat   198 PKKPKTNASISETG--RG-SASSLNMSPSEASSQVVLSNMNTSSIQSAAGKPSLRSCPKCNVKFS 259

  Fly   654 -------------PGSTNQTKGDRATTSSSKSLSKSLIAKGLGKKPKEKDEKIPMVIKKEEDDLR 705
                         |...|:.. :...:.:||::|:::|  |..|      ||:.|::
  Rat   260 LLDPLKCHMKRCCPDMINKFL-ETLKSENSKAVSRAII--GSDK------EKLIMLV-------- 307

  Fly   706 GLEELYYGISDGTDEYHEIFPYSTPRTVHNELAKTVECPICLNGDSFDSNEKLQTHLVSHISPEG 770
              .:.|||..:||.|..:..|            .|.:|..|..  ...:|.:...|:..|:..|.
  Rat   308 --SDFYYGRHEGTIEEDQKAP------------TTFKCFSCTK--VLKNNIRFMNHMKHHLEFEK 356

  Fly   771 KQHQ-----FQCLFCLEKHPTESVLAKHNQIMHPTETKTEGSPSYYCLICQQRHNSLHLLTAHLQ 830
            :.::     ..|..|..::|....|..|.:..|     |....|..|.||:....:.|||..|::
  Rat   357 QNNETWESHTTCQHCYRQYPNPFQLQCHIESTH-----TPHDFSTICKICELSFETEHLLLQHMK 416

  Fly   831 KVHSTLELPYWCHSCGYRSSSHRDLVRHFYDDHKHQNFLQCPYCLDIFYFSKLGVVNQLRIEHYF 895
            ..|...|:||.|..|.:|||...|:..||...|::...|.||:||.:   |::...   .:.||.
  Rat   417 DTHKPGEMPYICQVCQFRSSIFSDVETHFRSSHENTKNLLCPFCLKV---SRMATP---YMNHYM 475

  Fly   896 MHLDEHINKRDPSLRCQKCSLSFLEKGDLKQHAVQHH-------------------------VSM 935
            .|..:.|      .||.||.|.||...:...|.::|.                         :..
  Rat   476 RHQKKGI------YRCPKCRLQFLTSKEKIDHKLEHRTFIKPKELEGLPPGTKVTIRASLGSIQS 534

  Fly   936 TKTNRPVRLLLNNSMLIPPPKIRT----------HHREQPPFSTYKRPVFFAFLEGK-------- 982
            ..::.|...:.:.|:.:..||.:|          :.:......|...|...:...||
  Rat   535 RSSSPPSSTIPSTSLQLSVPKSKTTTTKNTTTKNNSKVSANKVTTTSPQTMSTTTGKTNASKPGT 599

  Fly   983 -------------------------------------TCAECNTDFASEETHYTGWLHCVKCNYQ 1010
                                                 ||.||::......:|::.:::|..|.|.
  Rat   600 GTTKSKAKPSNKQKRQRTRKNKFSIDLRNLRCHQGTHTCIECHSKIKDFSSHFSTYINCDFCKYT 664

  Fly  1011 TCCERAQFRHGVECNGNFVDAMEVNMPQEMHCI-----------------CGFA--TGNGNKMAQ 1056
            |.|.:|...|....|.:         |.:..||                 |.|.  |...::||:
  Rat   665 TNCNKAFTNHMSSHNDH---------PSKQLCIFKKHSRALRGITLVCLKCDFLADTSGLDRMAK 720

  Fly  1057 HLANCGLSTCYPSLEAASE 1075
            ||......||...:|..:|
  Rat   721 HLNQRKTHTCQVVIENVTE 739

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
row	NP_001260992.1	C2H2 Zn finger	777..798	CDD:275368	5/20 (25%)
		C2H2 Zn finger	812..833	CDD:275368	7/20 (35%)
		C2H2 Zn finger	842..858	CDD:275368	6/15 (40%)
Zfp280c	XP_006257603.1	DUF4195	62..237	CDD:404681	24/106 (23%)
		C2H2 Zn finger	368..389	CDD:275368	5/20 (25%)
		C2H2 Zn finger	398..419	CDD:275368	7/20 (35%)
		C2H2 Zn finger	428..446	CDD:275368	7/17 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm45293
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1818
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910