DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment row and pzf-1

DIOPT Version :9

Sequence 1:NP_001260992.1 Gene:row / 36685 FlyBaseID:FBgn0033998 Length:1301 Species:Drosophila melanogaster
Sequence 2:NP_001256688.1 Gene:pzf-1 / 188142 WormBaseID:WBGene00011505 Length:504 Species:Caenorhabditis elegans


Alignment Length:462 Identity:89/462 - (19%)
Similarity:152/462 - (32%) Gaps:113/462 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   680 KGLGKKPKEKDEKIPMVIKKEEDDLRGLEELYYGISDGTDEYHEIFPYSTPRTVHNEL--AKTVE 742
            |..|:....|...:||.....|......:.     .:|:|:.....|...|....|.:  |.:::
 Worm    91 KSTGRPGLLKPLAMPMTAPAREASALNTDP-----QNGSDDVPHSSPSPVPMIAENSIIQASSLK 150

  Fly   743 CPICLNGDSFDSNEKLQTHLVSHISPEGKQHQFQCLFCLEKHPTESVLAKHNQIMHPTETKTEGS 807
            .....:.|...::......|||....|    :..|.||.:....|..|.:|.:..|.|       
 Worm   151 MEPIESADRSSASTSTPRTLVSGTPRE----KIPCGFCGKDFFHEGSLREHRRRFHMT------- 204

  Fly   808 PSYYCLICQQRHNSLHLLTAHLQKVHSTLELPYWCHSCGYRSSSHRDLVRHFYDDHKHQNFLQC- 871
             .:.||:|.::......:..|::..|: ::..|.|..|.:...:...|:.|          ..| 
 Worm   205 -GHTCLLCNRQIPENETVRDHMKSQHN-IKKVYNCLCCNWTFLNQVHLISH----------KTCL 257

  Fly   872 -----PYCLDIFYFSKLGVVNQLRIEHYFMHLDEHINKRDPS----------LRCQKCSLSFLEK 921
                 |.|.. .:...|.:.....|..:|....|..:..|.|          |.|:.|...|..:
 Worm   258 KQTGKPCCRP-GHMEPLAIPRTASIRQFFTLKTETQSGDDDSAAGSQLFSARLSCKSCGKFFYSE 321

  Fly   922 GDLKQHAVQHHVSMTKTNRPVRLLLNNSMLIPPPKIRT--HHREQPPFSTYKRPVFFAFLEGKTC 984
            ..|.:|..|.|:|     ..|.:|.|:.|    ||..|  .|.|:      :..:...|    .|
 Worm   322 RSLSKHHRQIHMS-----GHVCVLCNHQM----PKTVTVQEHMEK------EHNIRLVF----NC 367

  Fly   985 AECNTDFASEETHYTGWLHCVKCNYQTCCERAQFRHGVECNGNFVDAMEVNMPQEMHCICGFATG 1049
            ..||..||:.        .|:..:.: |.::|         |:..:...|.:|:..         
 Worm   368 RCCNWSFATR--------RCLMSHVE-CLKKA---------GDARNVKPVAIPRMA--------- 405

  Fly  1050 NGNKMAQHLANCGLSTCYPSLEAASENA-------------VKRNM---LDMLGLVRRDGETSGE 1098
             .:.:.|.|....... ||...|||..:             .|:|:   .|.:.::..:|..|.|
 Worm   406 -ADSILQSLKESEAQE-YPDFSAASTTSSGPASTLKTPRMDFKKNLKICTDAVQILVGNGLFSNE 468

  Fly  1099 GADISET 1105
            ....:||
 Worm   469 QLAQTET 475

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rowNP_001260992.1 C2H2 Zn finger 777..798 CDD:275368 6/20 (30%)
C2H2 Zn finger 812..833 CDD:275368 4/20 (20%)
C2H2 Zn finger 842..858 CDD:275368 3/15 (20%)
pzf-1NP_001256688.1 COG5236 <13..>62 CDD:227561
C2H2 Zn finger 181..202 CDD:275368 6/20 (30%)
C2H2 Zn finger 208..229 CDD:275368 4/20 (20%)
C2H2 Zn finger 237..253 CDD:275368 3/15 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24408
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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