DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment row and Zbtb48

DIOPT Version :9

Sequence 1:	NP_001260992.1	Gene:	row / 36685	FlyBaseID:	FBgn0033998	Length:	1301	Species:	Drosophila melanogaster
Sequence 2:	XP_017175372.1	Gene:	Zbtb48 / 100090	MGIID:	2140248	Length:	767	Species:	Mus musculus

Alignment Length:	406	Identity:	73/406 - (17%)
Similarity:	135/406 - (33%)	Gaps:	103/406 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   567 QRLYQVATNPFKDWSILPANYKETPANAAPKRLKKPINDADYVVSNKIPKKEKDRDIASSGVKRG 631
            ||:|...|.   ...:|||.:.|.....           .|:..:..:.....:||......|..
Mouse    82 QRIYGDGTG---GSVVLPAGFAEIFGLL-----------LDFFYTGHLALTSGNRDQVLLAAKEL 132

  Fly   632 RPPNAL---GTPPPQLPI---KKGPGRPPGSTNQTKGDRATTSSSKSLSKSLIAKGLGKKPKEKD 690
            |.|.|:   .:..||..:   :.|.|:|.....::.....|....:.:.::|....:.::|::.:
Mouse   133 RVPEAVELCQSFQPQTSVGQAQSGLGQPASQDVKSHLKEPTDLDEEEVFRTLSLASVDQEPRDTE 197

  Fly   691 E----------------KIPMVIK------KEEDDLRGLEELYYGISDGTDEYHEIFPYSTPRTV 733
            :                |:...:|      ||.:|.:                      ..||..
Mouse   198 QPQLGTPAQSTTAFLCGKLTQALKPSPSEDKESEDCK----------------------EPPRPF 240

  Fly   734 H----------NELAKTVECPICLNGDSFDSNEKLQTHLVSHISPEGKQHQFQCLFCLEKHPTES 788
            .          ||....|:.....:||.....|.:.|...|.:..:      .|       ..|.
Mouse   241 EAGGAPLQGESNEWEVVVQVEDDRDGDYVSEPETVLTRRKSKVIRK------PC-------AAEP 292

  Fly   789 VLAKHNQIMHPTETKTEGSPSYYCLICQQRHNSLHLLTAHLQKVHSTLELPYWCHSCGYRSSSHR 853
            .|...:....||:::...:....|..|.::..|.:.|..|.:|  .|.|.|:.|..||.......
Mouse   293 ALGAGSLTAEPTDSRKGAAVPVECPTCHKKFLSKYYLKVHNRK--HTGEKPFECPKCGKCYFRKE 355

  Fly   854 DLVRHFYDD--HKHQNFLQCPYCLDIFYFSKLGVVNQLRIEHYFMHLDEHINKRDPSLRCQKCSL 916
            :|:.|...:  ::.:....|..|.:.|         :.|:| ..:|:..|..  :...:|..||.
Mouse   356 NLLEHEARNCMNRSEQVFTCSVCQETF---------RRRME-LRLHMVSHTG--EMPYKCSSCSQ 408

  Fly   917 SFLEKGDLKQHAVQHH 932
            .|::|.||:.|.::.|
Mouse   409 QFMQKKDLQSHMIKLH 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
row	NP_001260992.1	C2H2 Zn finger	777..798	CDD:275368	3/20 (15%)
		C2H2 Zn finger	812..833	CDD:275368	6/20 (30%)
		C2H2 Zn finger	842..858	CDD:275368	4/15 (27%)
Zbtb48	XP_017175372.1	BTB_POZ_ZBTB48_TZAP_KR3	38..145	CDD:349541	15/76 (20%)
		C2H2 Zn finger	316..336	CDD:275368	6/21 (29%)
		zf-H2C2_2	328..351	CDD:372612	9/24 (38%)
		C2H2 Zn finger	344..395	CDD:275368	11/60 (18%)
		zf-H2C2_2	387..410	CDD:372612	6/25 (24%)
		C2H2 Zn finger	403..424	CDD:275368	8/20 (40%)
		PHA03247	<426..583	CDD:223021
		zf-H2C2_2	586..610	CDD:372612
		C2H2 Zn finger	602..623	CDD:275368
		C2H2 Zn finger	631..651	CDD:275368
		zf-H2C2_2	644..668	CDD:372612
		zf-C2H2	657..679	CDD:333835
		C2H2 Zn finger	659..679	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24408
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010