DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11807 and AT3G17920

DIOPT Version :9

Sequence 1:	NP_001260990.1	Gene:	CG11807 / 36683	FlyBaseID:	FBgn0033996	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_188419.2	Gene:	AT3G17920 / 819843	AraportID:	AT3G17920	Length:	1010	Species:	Arabidopsis thaliana

Alignment Length:	371	Identity:	91/371 - (24%)
Similarity:	149/371 - (40%)	Gaps:	77/371 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 LQDLAKLFNESGDALLSSKKEYNLSALEVYAISERL-SLPCPPSLDRGGKYDF-----SHVLDF- 180
            |::|.:..:|..|.|:.......|:...::.:..|| ||.....:..|...|:     |.:.||
plant    10 LENLQRFLDEKADLLIDGTDVLKLNPAGLHYVHLRLESLRELELMLSGAPVDYLRAYVSDIGDFR 74

  Fly   181 -------------CTQLVALVVTPVKDNASYAQDYNTVDVPIDRSNIIPNRLSFNLNAFRNLKTL 232
                         ..::|:.:.:|.:|                     |..||  |..|..||.|
plant    75 ALEQLRRILRLLPSLKVVSSLPSPARD---------------------PTPLS--LLPFSKLKVL 116

  Fly   233 KFSA--LSTENIVDIELLKPTLQTICVHNTTIQNINQVLLCDNLHKHCDVPSLLPETILASPSGS 295
            :...  |||.:...:..|:.||:.:..||:|          |.| :|. ..|.:.| |..||.
plant   117 ELRGCDLSTSSAKGLLELRHTLEKLICHNST----------DAL-RHV-FASRIAE-IKDSPQ-- 166

  Fly   296 GPSTSNGSALVSADAWQEITELDLTGNLLTQIDGSVRTAPKLRRLILDQNRIRTVQNLAELPQLQ 360
                           |.::..:....|.|..:|.|::..|.:..|.|.:|:...|.||....:|:
plant   167 ---------------WNKLAFISCACNRLVLMDESLQLLPAVESLDLSRNKFAKVDNLRRCNKLK 216

  Fly   361 LLSLSGNLIAECVDWHLTMGNLVTLKLAQNKIKTLSGLRKLLSLVNLDLSSNQIEELDEVNHVAN 425
            .|.|..|.:.:.........:||.|.|..|.:.||.|:..|.||..||:|.|.|.:..|:..:.:
plant   217 HLDLGFNQLRKISHLSEVSCHLVKLVLRNNALTTLRGIENLKSLEGLDVSFNLISDFSELEFLGS 281

  Fly   426 LPLLETLRLTGNPLAGSVDYRSRVLARFHERAAEISLDNEP-GNQQ 470
            |..|..|.|.|||:..:..||:.||:..: ...::.||.:. ||::
plant   282 LSFLTDLWLEGNPICCARWYRAHVLSYVY-LPNDLKLDGKHIGNRE 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11807	NP_001260990.1	PX_IRAS	8..126	CDD:132785	1/2 (50%)
		leucine-rich repeat	315..336	CDD:275380	4/20 (20%)
		LRR_8	335..414	CDD:290566	26/78 (33%)
		leucine-rich repeat	337..381	CDD:275380	10/43 (23%)
		LRR_4	381..422	CDD:289563	17/40 (43%)
		leucine-rich repeat	382..403	CDD:275380	9/20 (45%)
		leucine-rich repeat	404..428	CDD:275380	8/23 (35%)
AT3G17920	NP_188419.2	leucine-rich repeat	51..78	CDD:275380	5/26 (19%)
		leucine-rich repeat	79..112	CDD:275380	8/55 (15%)
		leucine-rich repeat	113..136	CDD:275378	7/22 (32%)
		LRR_RI	<189..297	CDD:238064	35/107 (33%)
		leucine-rich repeat	193..214	CDD:275378	6/20 (30%)
		leucine-rich repeat	215..237	CDD:275378	4/21 (19%)
		LRR_8	237..295	CDD:290566	23/57 (40%)
		leucine-rich repeat	238..259	CDD:275378	9/20 (45%)
		leucine-rich repeat	260..284	CDD:275378	8/23 (35%)
		leucine-rich repeat	285..297	CDD:275378	6/11 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1859
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810