DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11807 and CG8800

DIOPT Version :9

Sequence 1:	NP_001260990.1	Gene:	CG11807 / 36683	FlyBaseID:	FBgn0033996	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_610483.1	Gene:	CG8800 / 35962	FlyBaseID:	FBgn0033408	Length:	188	Species:	Drosophila melanogaster

Alignment Length:	169	Identity:	46/169 - (27%)
Similarity:	78/169 - (46%)	Gaps:	16/169 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   311 WQE----------ITELDLTGNLLTQIDGSVRTAPKLRRLILDQNRIRTVQNLAELPQLQLLSLS 365
            |:|          :.:|......:.::|.::.|..:..|:.:..|.|..:..|:.:..|::||||
  Fly    14 WEEREQQNSLTAKVIDLQFQWPPIEKMDSTLGTLVQCERISMSTNMIEKIFGLSGMKCLKVLSLS 78

  Fly   366 GNLIAECVDWHLTMGNLVTLKLAQNKIKTLSGLRKLLSLVNLDLSSNQIEELDEVNHVANLPLLE 430
            .|.|.:..........|..|.|:.|.|:.:.||..|..|..|.:|:|.|::..|.|.:|.:..||
  Fly    79 RNYIKQISGLEAVAETLEELWLSYNLIEKIKGLTGLKCLKVLYISNNLIKDWSEFNRLAEIESLE 143

  Fly   431 TLRLTGNPLAGSVD---YRSRVLARFHERAAEISLDNEP 466
            .|.:.||||:..:|   :|:..:.|.   .....||.||
  Fly   144 DLVVVGNPLSEGLDEPTWRAECIKRL---PTIRKLDGEP 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11807	NP_001260990.1	PX_IRAS	8..126	CDD:132785
		leucine-rich repeat	315..336	CDD:275380	3/20 (15%)
		LRR_8	335..414	CDD:290566	23/78 (29%)
		leucine-rich repeat	337..381	CDD:275380	11/43 (26%)
		LRR_4	381..422	CDD:289563	14/40 (35%)
		leucine-rich repeat	382..403	CDD:275380	8/20 (40%)
		leucine-rich repeat	404..428	CDD:275380	8/23 (35%)
CG8800	NP_610483.1	PPP1R42	37..180	CDD:411060	43/146 (29%)
		leucine-rich repeat	50..71	CDD:275380	4/20 (20%)
		leucine-rich repeat	95..116	CDD:275380	8/20 (40%)
		leucine-rich repeat	117..141	CDD:275380	8/23 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR15454
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100