DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11807 and Sgk3

DIOPT Version :9

Sequence 1:NP_001260990.1 Gene:CG11807 / 36683 FlyBaseID:FBgn0033996 Length:491 Species:Drosophila melanogaster
Sequence 2:NP_001032848.1 Gene:Sgk3 / 170755 MGIID:2182368 Length:496 Species:Mus musculus


Alignment Length:468 Identity:97/468 - (20%)
Similarity:165/468 - (35%) Gaps:137/468 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 TVTVPKFSNE--SSSGGVTYYDIKVRVGKVEWLVERRYRDFANLHEKLVGEISISKKLLPPKKLV 74
            :|::|. |:|  ......|.|.:.|.||:.||.|.|||.:|..|:..|..:.......:|.|::.
Mouse    15 SVSIPS-SDEHREKKKRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNSLKKQFPAMALKIPAKRIF 78

  Fly    75 G-NKQPSFLEQRREQLEIYLQELLIYFRTELPRALAEFLDFNKYDI-IYLLQDLAKLFNESGDAL 137
            | |..|.|::|||..|..::|.|:.|  .||         :|..|: .:|..|..:..::     
Mouse    79 GDNFDPDFIKQRRAGLNEFIQNLVRY--PEL---------YNHPDVRAFLQMDSPRHQSD----- 127

  Fly   138 LSSKKEYNLSALEVYAISERLSL-PCPPSLDRGGKYDFSHVLDFCTQLVALVVTPVKDNASYAQD 201
             .|:.|...|..:.::.|..::| |......:...:||..|:...:....|:.....|...||  
Mouse   128 -PSEDEDERSTSKPHSTSRNINLGPTGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYA-- 189

  Fly   202 YNTVDVPIDRSNIIPNRL-SFNLNAFRN--LKTLK--------FSALSTEN---IVD-------- 244
                 |.:.:..|:.||. ..::.|.||  ||.:|        :|..:||.   ::|        
Mouse   190 -----VKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELF 249

  Fly   245 ---------------------------IELLKPTLQTICVHNTTIQNINQVLLCD-NLHKH---- 277
                                       :..:|...:.:...|..:.::..|:|.| .|.|.    
Mouse   250 FHLQRERSFPEPRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSMGHVVLTDFGLCKEGIAI 314

  Fly   278 -------CDVPS-LLPETILASPSGSGPSTSNGSALVSADAW------------------QEITE 316
                   |..|. |.||.|...|..:           :.|.|                  :::.|
Mouse   315 SDTTTTFCGTPEYLAPEVIRKQPYDN-----------TVDWWCLGAVLYEMLYGLPPFYCRDVAE 368

  Fly   317 L--DLTGNLLTQIDGSVRTAPKLRRLILDQNRIRTVQNLAELPQLQLLSLSGNLIAECVDWHLTM 379
            :  ::....|....|...||..:...:|::||    ||.....: ..|.:..:...|.:.|    
Mouse   369 MYDNILHKPLNLRPGVSLTAWSILEELLEKNR----QNRLGAKE-DFLEIQNHPFFESLSW---- 424

  Fly   380 GNLVTLKLAQNKI 392
                 ..|.|.||
Mouse   425 -----TDLVQKKI 432

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11807NP_001260990.1 PX_IRAS 8..126 CDD:132785 36/117 (31%)
leucine-rich repeat 315..336 CDD:275380 5/22 (23%)
LRR_8 335..414 CDD:290566 12/58 (21%)
leucine-rich repeat 337..381 CDD:275380 8/43 (19%)
LRR_4 381..422 CDD:289563 4/12 (33%)
leucine-rich repeat 382..403 CDD:275380 4/11 (36%)
leucine-rich repeat 404..428 CDD:275380
Sgk3NP_001032848.1 PX_CISK 12..120 CDD:132780 36/116 (31%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 121..157 6/41 (15%)
S_TKc 162..419 CDD:214567 48/279 (17%)
STKc_SGK3 165..490 CDD:270755 52/300 (17%)
Nuclear localization signal. /evidence=ECO:0000250 195..205 3/9 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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