Protein Alignment CG11807 and nisch

DIOPT Version :10

• Sequence 1: NP_611017.1
• Gene: CG11807 / 36683
• FlyBaseID: FBgn0033996
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: XP_031755760.1
• Gene: nisch / 100170568
• XenbaseID: XB-GENE-5968394
• Length: 1362
• Species: Xenopus tropicalis
• Alignment Length: 471
• Identity: 163/471 - (34%)
• Similarity: 250/471 - (53%)
• Gaps: 44/471 - (9%)

  Fly    28 TYYDIKVRVGKVEWLVERRYRDFANLHEKLVGEISISKKLLPPKKLVGNKQPSFLEQRREQLEIY 92
            |.|.|::|.|...|.|..||.||.:|||||..|..|.:.||||||::|....|.:|:|::.||:|
 Frog    24 TVYIIQLRAGSFHWEVRHRYSDFYDLHEKLTAENKIERNLLPPKKMIGKNSRSLVEKRQKDLELY 88

  Fly    93 LQELLIYFRTELPRALAEFLDFNKYDIIYLLQDLAKLFNESGDALLSSKKEYNLSALEVYAISER 157
            ||.||..|...:|:|||.||.|:.|:|..:...||:.....|:.||.:.:.:.::.|::||:::.
 Frog    89 LQTLLGTFPLAVPKALARFLHFHLYEIHGIAAVLAEELFHKGEQLLLAGEVFTVTPLQLYAVTQL 153

  Fly   158 LSLPCPPSLDRGGKYDFSHVLDFCTQLVALVVTPVKDNASYAQDYNTVDVPIDRSNIIPNRLSFN 222
            |....|.......:.|..|::||..:|..|.::....             |:..|||....|..:
 Frog   154 LRRAKPTCSTGDARNDLGHIMDFACRLKYLRISGRTG-------------PVGTSNIHEQSLPCD 205

  Fly   223 LNAFRNLKTLKFSALSTENIVDIELLKPTLQTICVHNTTIQNINQVLLCDNLHKHCDVPS----L 283
            |:.|::|..::.|..:...:..:...:.:|.||.:                   ||...|    |
 Frog   206 LSIFKSLCQIEVSQCNARLLSGLTSCRRSLATISI-------------------HCSASSMKDIL 251

  Fly   284 LPETI---LASPSGSGPSTSNGSALVS-ADAWQEITELDLTGNLLTQIDGSVRTAPKLRRLILDQ 344
            :||..   ...|.|..|    ||.:.: ...|:.:|.|||:.|.::.||.||:..|::..|....
 Frog   252 VPEAYDFEQWEPEGVAP----GSPITAVVPKWKVLTTLDLSHNRISCIDESVKLIPEIEFLDFSH 312

  Fly   345 NRIRTVQNLAELPQLQLLSLSGNLIAECVDWHLTMGNLVTLKLAQNKIKTLSGLRKLLSLVNLDL 409
            |.|.|::||..|..|..|.||.|.:|:....:..:||:.||.||.|.:::|.||.||.|||||||
 Frog   313 NDISTIENLQHLYNLIHLDLSYNKLADLTGIYTKVGNIKTLSLAGNVLESLRGLNKLYSLVNLDL 377

  Fly   410 SSNQIEELDEVNHVANLPLLETLRLTGNPLAGSVDYRSRVLARFHERAAEISLDNEPGNQQELDT 474
            |.|:||:|:||.::..||.||.:.|.||||....|||::|||.|.:||:|:.||:....::||||
 Frog   378 SQNRIEQLEEVRNIGGLPCLEGVLLAGNPLTVIPDYRTKVLALFGDRASEVCLDSTRTTEKELDT 442

  Fly   475 ALVLSALLQSKQRQQQ 490
            ..||.|:.:|:..:.:
 Frog   443 VEVLKAIQKSRDARNK 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11807	NP_611017.1	PX_IRAS	8..126	CDD:132785	45/97 (46%)
		PPP1R42	<314..451	CDD:455733	62/136 (46%)
		leucine-rich repeat	315..336	CDD:275380	9/20 (45%)
		leucine-rich repeat	337..381	CDD:275380	13/43 (30%)
		leucine-rich repeat	382..403	CDD:275380	10/20 (50%)
		leucine-rich repeat	404..428	CDD:275380	14/23 (61%)
nisch	XP_031755760.1	PX_IRAS	16..122	CDD:132785	45/97 (46%)
		LRR	<282..>408	CDD:443914	57/125 (46%)
		leucine-rich repeat	282..304	CDD:275380	9/21 (43%)
		leucine-rich repeat	305..326	CDD:275380	7/20 (35%)
		leucine-rich repeat	327..349	CDD:275380	6/21 (29%)
		leucine-rich repeat	350..371	CDD:275380	10/20 (50%)
		leucine-rich repeat	372..396	CDD:275380	14/23 (61%)