DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GPHR and GTG1

DIOPT Version :9

Sequence 1:	NP_611016.2	Gene:	GPHR / 36682	FlyBaseID:	FBgn0033995	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_001031235.1	Gene:	GTG1 / 842807	AraportID:	AT1G64990	Length:	468	Species:	Arabidopsis thaliana

Alignment Length:	458	Identity:	184/458 - (40%)
Similarity:	275/458 - (60%)	Gaps:	23/458 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 GDCVIVFVSQMIFFAGGWLFFNKELFKHYEIRHISVQLIFSSTFALSITMFELIIFEIIDVLESS 69
            |..||..:| ::.:||.| |.|:.|:|.||.:...||:|||..||.|..:.:|::||||.||...
plant    10 GTVVIASLS-LLGWAGLW-FLNRRLYKEYEEKRALVQIIFSVVFAFSCNLLQLVLFEIIPVLSRE 72

  Fly    70 SRYFHWRLGLTLLLFMTTAVIPIYICYSVIHSISFFSDKWVRILTTFCWF-IFIYGLWRIGDPFP 133
            :|..:|::.|..|:.:...::|.|.||.::.:.....::  ..:..|.:. .|:|..||:|..||
plant    73 ARMINWKVDLFCLILLLVFMLPYYHCYLMLRNSGVRRER--ASVGAFLFLSAFLYAFWRMGVHFP 135

  Fly   134 LLSASHGIFTIEQGVSRISVIGVTVMAILSGFGAVNYPYTSMSYFIKPVSRNDIICFERRLALTV 198
            :.||..|.||:.|.||||.|||||:||:||||||||.||:.:|.||:.:...|||..||:|..:.
plant   136 MPSADKGFFTMPQLVSRIGVIGVTLMAVLSGFGAVNLPYSYISLFIREIEEADIISLERQLIQST 200

  Fly   199 EMLSAKKRKIAMAIYNHNKLNPSKP---------RIWDMLASAVQRNTNSGEDINQLKQEVYGLE 254
            |...|||:||.:......:...|:.         ||...:..:|| :....:||..|:.||..||
plant   201 ETCIAKKKKIILCQLEVERNQGSEENQKRSSFFRRIVGTVVRSVQ-DDQKEQDIKILEAEVEALE 264

  Fly   255 ELLRSVFLELSSLKNMEERQRWSQTLKGKYFNVLGHFFSVYCVYKIFMCCINIIFDRVGRKDPVT 319
            ||.:.:|||:..|:..::...:|:|.||...|:||:..|:|||||:.....:::|...|.|||||
plant   265 ELSKQLFLEVYELRQAKDAAAYSRTWKGHVQNLLGYACSIYCVYKMLKSLQSVVFKEAGTKDPVT 329

  Fly   320 RGLEIAIHWCGFNIDFAFWNQHISFLLVGCIVITSIRGLLLTLTKFFY---RISSSKSSNIIVLI 381
            ..:.|.:......:|.|..:|:||.|.:|.:::.|:||.|..|.|||:   |:.|..||| :||.
plant   330 TMISIFLRLFDIGVDAALLSQYISLLFIGMLIVISVRGFLTNLMKFFFAVSRVGSGSSSN-VVLF 393

  Fly   382 LGQIMGMYFCSSVLLMRMNMPAEYRVIITEVL-GNLHFNFYHRWFDVIFLVSALTTIIVL---YL 442
            |.:||||||.||:||:|.::..|||.|||:|| |::.|:|||||||.||:.||..::::|   |.
plant   394 LSEIMGMYFLSSILLIRKSLRNEYRGIITDVLGGDIQFDFYHRWFDAIFVASAFLSLVLLSAHYT 458

  Fly   443 SRK 445
            ||:
plant   459 SRQ 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GPHR	NP_611016.2	GPHR_N	141..208	CDD:289314	37/66 (56%)
GPHR	NP_611016.2	ABA_GPCR	277..443	CDD:289215	78/172 (45%)
GTG1	NP_001031235.1	GPHR_N	143..210	CDD:372172	37/66 (56%)
GTG1	NP_001031235.1	ABA_GPCR	285..457	CDD:372104	77/172 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	153	1.000	Domainoid score	I1368
eggNOG	1	0.900	-	-		E1_KOG2417
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9475
Inparanoid	1	1.050	318	1.000	Inparanoid score	I714
OMA	1	1.010	-	-		QHG55010
OrthoDB	1	1.010	-	-		D1065554at2759
OrthoFinder	1	1.000	-	-		FOG0003368
OrthoInspector	1	1.000	-	-		otm3021
orthoMCL	1	0.900	-	-		OOG6_103122
Panther	1	1.100	-	-	LDO	PTHR15948
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2255
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840