DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GPHR and GTG2

DIOPT Version :9

Sequence 1:	NP_611016.2	Gene:	GPHR / 36682	FlyBaseID:	FBgn0033995	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_001190854.1	Gene:	GTG2 / 828874	AraportID:	AT4G27630	Length:	491	Species:	Arabidopsis thaliana

Alignment Length:	481	Identity:	177/481 - (36%)
Similarity:	270/481 - (56%)	Gaps:	50/481 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VIVFVSQMIFFAGGWLFFNKELFKHYEIRHISVQLIFSSTFALSITMFELIIFEIIDVLESSSRY 72
            ::|..|..:..:.|..|.|:.|:|.||.:...||:|||..||.|..:.:|::||||.||...:|.
plant    11 MLVIGSLCLLGSAGLWFLNRRLYKEYEEKRALVQIIFSVVFAFSCNLLQLVLFEIIPVLSREARM 75

  Fly    73 FHWRLGLTLLLFMTTAVIPIYICYSVIHSISFFSDK----WVRILTTFCWFIFIYGLWRIGDPFP 133
            .:|::.|..|:.:...::|.|.||.::.:.....::    .:..||.     |:|..||:|..||
plant    76 VNWKVDLFCLIVLLVFMLPYYHCYLMLRNTGVRRERAAVGALLFLTA-----FLYAFWRMGIHFP 135

  Fly   134 LLSASHGIFTIEQGVSRISVIGVTVMAILSGFGAVNYPYTSMSYFIKPVSRNDIICFERRLALTV 198
            :.| ..|.|::.|.||||.|||||:||:||||||||.||:.:|.||:.:..::|...||:|..::
plant   136 MPS-DKGFFSMPQLVSRIGVIGVTLMAVLSGFGAVNLPYSYISLFIREIEESEIKSLERQLMQSM 199

  Fly   199 EMLSAKKRKI---------AMAIYNHNKLNPSKPRIWDMLASAVQRNTNSGE------------- 241
            |...|||:||         ::....|.|......|....:..:||.:.....
plant   200 ETCIAKKKKILLCQVEVERSLVSEEHQKGKSFFRRFVGTVVRSVQDDQKEQVQLVYCWDNKVVEL 264

  Fly   242 ----------DINQLKQEVYGLEELLRSVFLELSSLKNMEERQRWSQTLKGKYFNVLGHFFSVYC 296
                      ||..::.||.|||||.:.:|||:..|:..::...:|:|.||...|.||:..|:||
plant   265 LQFSPCCQIIDIKLMEAEVEGLEELSKQLFLEIYELRQAKDAAAFSRTWKGHVQNFLGYACSIYC 329

  Fly   297 VYKIFMCCINIIFDRVGRKDPVTRGLEIAIHWCGFNIDFAFWNQHISFLLVGCIVITSIRGLLLT 361
            |||:.....:::|...|.|||||..:.|.:.:....:|.|..:|:||.|.:|.:::.|:||.|..
plant   330 VYKMLKSLQSVVFKEAGTKDPVTMMISIFLQFFDIGVDAALLSQYISLLFIGMLIVISVRGFLTN 394

  Fly   362 LTKFFY---RISSSKSSNIIVLILGQIMGMYFCSSVLLMRMNMPAEYRVIITEVL-GNLHFNFYH 422
            |.|||:   |:.|..||| :||.|.:||||||.||:||:|.::..|||.|||:|| |::.|:|||
plant   395 LMKFFFAVSRVGSGSSSN-VVLFLSEIMGMYFLSSILLIRKSLRNEYRGIITDVLGGDIQFDFYH 458

  Fly   423 RWFDVIFLVSALTTIIVL---YLSRK 445
            ||||.||:.||..::::|   |.||:
plant   459 RWFDAIFVASAFLSLLLLSAHYTSRQ 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GPHR	NP_611016.2	GPHR_N	141..208	CDD:289314	34/66 (52%)
GPHR	NP_611016.2	ABA_GPCR	277..443	CDD:289215	78/172 (45%)
GTG2	NP_001190854.1	GPHR_N	142..209	CDD:289314	34/66 (52%)
GTG2	NP_001190854.1	ABA_GPCR	308..466	CDD:289215	73/158 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	153	1.000	Domainoid score	I1368
eggNOG	1	0.900	-	-		E1_KOG2417
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9475
Inparanoid	1	1.050	318	1.000	Inparanoid score	I714
OMA	1	1.010	-	-		QHG55010
OrthoDB	1	1.010	-	-		D1065554at2759
OrthoFinder	1	1.000	-	-		FOG0003368
OrthoInspector	1	1.000	-	-		otm3021
orthoMCL	1	0.900	-	-		OOG6_103122
Panther	1	1.100	-	-	O	PTHR15948
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2255
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840