Protein Alignment GPHR and GPR89B

DIOPT Version :10

• Sequence 1: NP_611016.2
• Gene: GPHR / 36682
• FlyBaseID: FBgn0033995
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_057418.1
• Gene: GPR89B / 51463
• HGNCID: 13840
• Length: 455
• Species: Homo sapiens
• Alignment Length: 449
• Identity: 257/449 - (57%)
• Similarity: 337/449 - (75%)
• Gaps: 7/449 - (1%)

  Fly     1 MAFLGDCVIVFVSQMIFFAGGWLFFNKELFKHYEIRHISVQLIFSSTFALSITMFELIIFEIIDV 65
            |:||.|..|:..||::||..|||||.::|||.||||...||:|||.|||.|.||||||||||:.|
Human     1 MSFLIDSSIMITSQILFFGFGWLFFMRQLFKDYEIRQYVVQVIFSVTFAFSCTMFELIIFEILGV 65

  Fly    66 LESSSRYFHWRLGLTLLLFMTTAVIPIYICYSVIHSISFFSDKWVRIL-TTFCWFIFIYGLWRIG 129
            |.||||||||::.|.::|.:...::|.||.|.::.:|.....:  |:| :...|..|:|..|::|
Human    66 LNSSSRYFHWKMNLCVILLILVFMVPFYIGYFIVSNIRLLHKQ--RLLFSCLLWLTFMYFFWKLG 128

  Fly   130 DPFPLLSASHGIFTIEQGVSRISVIGVTVMAILSGFGAVNYPYTSMSYFIKPVSRNDIICFERRL 194
            ||||:||..|||.:|||.:||:.|||||:||:||||||||.|||.||||::.|:..||:..||||
Human   129 DPFPILSPKHGILSIEQLISRVGVIGVTLMALLSGFGAVNCPYTYMSYFLRNVTDTDILALERRL 193

  Fly   195 ALTVEMLSAKKRKIAMA---IYNHNKLNPSKPRIWDMLASAVQRNTNSGEDINQLKQEVYGLEEL 256
            ..|::|:.:||:::|||   ::...:::......|.|:.| |..:.:..|::..::|||..||||
Human   194 LQTMDMIISKKKRMAMARRTMFQKGEVHNKPSGFWGMIKS-VTTSASGSENLTLIQQEVDALEEL 257

  Fly   257 LRSVFLELSSLKNMEERQRWSQTLKGKYFNVLGHFFSVYCVYKIFMCCINIIFDRVGRKDPVTRG 321
            .|.:|||.:.|...:||..:|:|.||||||.||:|||:|||:||||..|||:|||||:.||||||
Human   258 SRQLFLETADLYATKERIEYSKTFKGKYFNFLGYFFSIYCVWKIFMATINIVFDRVGKTDPVTRG 322

  Fly   322 LEIAIHWCGFNIDFAFWNQHISFLLVGCIVITSIRGLLLTLTKFFYRISSSKSSNIIVLILGQIM 386
            :||.:::.|...|..||:|||||:|||.|::|||||||:|||||||.||||||||:|||:|.|||
Human   323 IEITVNYLGIQFDVKFWSQHISFILVGIIIVTSIRGLLITLTKFFYAISSSKSSNVIVLLLAQIM 387

  Fly   387 GMYFCSSVLLMRMNMPAEYRVIITEVLGNLHFNFYHRWFDVIFLVSALTTIIVLYLSRK 445
            ||||.|||||:||:||.|||.|||||||.|.|||||||||||||||||::|:.|||:.|
Human   388 GMYFVSSVLLIRMSMPLEYRTIITEVLGELQFNFYHRWFDVIFLVSALSSILFLYLAHK 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GPHR	NP_611016.2	GPHR_N	141..208	CDD:463623	39/66 (59%)
		ABA_GPCR	277..445	CDD:463577	123/167 (74%)
GPR89B	NP_057418.1	GPHR_N	140..207	CDD:463623	39/66 (59%)
		ABA_GPCR	276..446	CDD:463577	123/169 (73%)