Protein Alignment igl and IQCN

DIOPT Version :10

• Sequence 1: NP_477060.1
• Gene: igl / 36681
• FlyBaseID: FBgn0013467
• Length: 240
• Species: Drosophila melanogaster
• Sequence 2: NP_001138776.1
• Gene: IQCN / 80726
• HGNCID: 29350
• Length: 1367
• Species: Homo sapiens
• Alignment Length: 196
• Identity: 42/196 - (21%)
• Similarity: 64/196 - (32%)
• Gaps: 74/196 - (37%)

  Fly     3 CNTSQELKTKDGAAMDAVSNGEPEPSAPPLEGESSKSSASNHTNHAKSSSIISNGEAKAANGGGA 67
            |:....|.::.|:          .||...|.|.|.::.   ||......:.:..|..:...|.||
Human  1229 CSVCHSLSSRIGS----------PPSVVMLVGSSPRTC---HTCGRTQPTRVVQGMGQGTEGPGA 1280

  Fly    68 VGGGSGKSEATNGIDRPCDKAAITEFNDDEDEAKAATKIQAVFRGHKVRETMKKSETKTATNNGS 132
            |...|....|.....:|            ..:.||||.||:.:||.|:|:.|::.:.
Human  1281 VSWASAYQLAALSPRQP------------HRQDKAATAIQSAWRGFKIRQQMRQQQM-------- 1325

  Fly   133 AAGAAPSAAAAEAAASAEPTKAELEAEFDPNDKDLCHAALKIQSTFRGHLARK-LVNKDA---PE 193
                                                 ||..:|:|:|||..|. |.|.:|   |.
Human  1326 -------------------------------------AAKIVQATWRGHHTRSCLKNTEALLGPA 1353

  Fly   194 D 194
            |
Human  1354 D 1354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
igl	NP_477060.1	Adgb_C_mid-like	<74..>129	CDD:412094	13/54 (24%)
		IQCD	99..>121	CDD:467745	11/21 (52%)
		IQ motif	104..122	CDD:412094	8/17 (47%)
		Adgb_C_mid-like	<169..>209	CDD:412094	13/30 (43%)
		IQ	169..185	CDD:197470	7/15 (47%)
		IQ motif	172..189	CDD:412094	7/17 (41%)
		globin helix A	196..209	CDD:412094
		IQCD	216..>238	CDD:467745
IQCN	NP_001138776.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	34..78
		IQCD	97..131	CDD:467745
		Herpes_BLLF1	<276..558	CDD:282904
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	283..324
		PHA03247	<351..862	CDD:223021
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	476..496
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	786..820
		IQ	1116..1134	CDD:459869
		IQCD	<1137..>1158	CDD:467745
		IQCD	<1161..>1181	CDD:467745