DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment igl and gap43

DIOPT Version :9

Sequence 1:	NP_477060.1	Gene:	igl / 36681	FlyBaseID:	FBgn0013467	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_571416.1	Gene:	gap43 / 30608	ZFINID:	ZDB-GENE-990415-87	Length:	194	Species:	Danio rerio

Alignment Length:	165	Identity:	46/165 - (27%)
Similarity:	65/165 - (39%)	Gaps:	41/165 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 RPCDK--AAITEFNDD-----EDEAKAATKIQAVFRGHKVRETMKKSE----------------- 123
            :|.:|  .|..|...|     |:..||||||||.||||..|:.||..|
Zfish     9 KPVEKNEEADQEIKQDGIKPEENAHKAATKIQASFRGHITRKKMKDGEKEEENGEVPEEQEEEKP 73

  Fly   124 --TKTATNN-------GSAAGAAPSAAAAEAAASAEPTKAEL-----EAEFDPNDKDLCHAALKI 174
              ..|.|..       .|.|..||..|||:.|.|..|.|.|:     |.| .|.:::...||...
Zfish    74 ADASTETQEDPKPEQPNSPANEAPPTAAADPAPSDTPAKEEVKEPQQEVE-KPKEEEQSSAAADE 137

  Fly   175 QSTFRGHLARKLVNKDAPEDEDIQEITKKVAEELD 209
            :....|:..::  .|:..:..|:.|...:...::|
Zfish   138 KPEEEGNAQKE--EKEEEKPADVPEAESQETHQID 170

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
igl	NP_477060.1	Adgb_C_mid-like	<74..>129	CDD:412094	23/71 (32%)
		IQ motif	104..122	CDD:412094	12/17 (71%)
		Adgb_C_mid-like	<169..>209	CDD:412094	6/39 (15%)
		IQ	169..185	CDD:197470	3/15 (20%)
		IQ motif	172..189	CDD:412094	1/16 (6%)
		globin helix A	196..209	CDD:412094	2/12 (17%)
		IQ	216..235	CDD:197470
gap43	NP_571416.1	IQ	33..53	CDD:279006	13/19 (68%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10699
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010