Protein Alignment igl and Gap43

DIOPT Version :10

• Sequence 1: NP_477060.1
• Gene: igl / 36681
• FlyBaseID: FBgn0013467
• Length: 240
• Species: Drosophila melanogaster
• Sequence 2: NP_058891.1
• Gene: Gap43 / 29423
• RGDID: 62071
• Length: 226
• Species: Rattus norvegicus
• Alignment Length: 173
• Identity: 50/173 - (28%)
• Similarity: 68/173 - (39%)
• Gaps: 40/173 - (23%)

  Fly    92 EFNDD-----------EDEA-KAATKIQAVFRGHKVRETMK----------KSETKTATNNGSAA 134
            |.||:           ||:| ||||||||.||||..|:.:|          ::|.|...:...|.
  Rat    12 EKNDEDQKIEQDGVKPEDKAHKAATKIQASFRGHITRKKLKDEKKGDAPAAEAEAKEKDDAPVAD 76

  Fly   135 G---------AAPSAAAAEAAASAEPTKA-ELEAEFDPNDKDLCHAALKIQSTFRGHLARKLVNK 189
            |         |...||.|.:..:.||:|| :..:|....:.|...:..|..|. ....|.|....
  Rat    77 GVEKKEGDGSATTDAAPATSPKAEEPSKAGDAPSEEKKGEGDAAPSEEKAGSA-ETESAAKATTD 140

  Fly   190 DAP----EDEDIQEITKKV---AEELDIDLTDPELNKAATKIQ 225
            ::|    ||...:|..|:.   |...|...|.|....||...|
  Rat   141 NSPSSKAEDGPAKEEPKQADVPAAVTDAAATTPAAEDAAKAAQ 183

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
igl	NP_477060.1	Adgb_C_mid-like	<74..>129	CDD:412094	22/58 (38%)
		IQCD	99..>121	CDD:467745	15/32 (47%)
		IQ motif	104..122	CDD:412094	11/27 (41%)
		Adgb_C_mid-like	<169..>209	CDD:412094	10/46 (22%)
		IQ	169..185	CDD:197470	3/15 (20%)
		IQ motif	172..189	CDD:412094	4/16 (25%)
		globin helix A	196..209	CDD:412094	3/15 (20%)
		IQCD	216..>238	CDD:467745	3/10 (30%)
Gap43	NP_058891.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..226		50/173 (29%)
		Neuromodulin_N	2..31	CDD:431370	5/18 (28%)
		IQ	30..52	CDD:197470	14/21 (67%)
		Neuromodulin	73..226	CDD:461961	28/112 (25%)