DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment igl and Spa17

DIOPT Version :9

Sequence 1:	NP_477060.1	Gene:	igl / 36681	FlyBaseID:	FBgn0013467	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	XP_011240741.2	Gene:	Spa17 / 20686	MGIID:	1333778	Length:	189	Species:	Mus musculus

Alignment Length:	131	Identity:	34/131 - (25%)
Similarity:	49/131 - (37%)	Gaps:	24/131 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 KDGAAMDAVSNGEPEPSA-----PPLEGESSKSSASN---HTNHAKSSSIISNGEAKAANGGGAV 68
            |..||....:.|.|.|::     ...:.|..|...||   |.||..........:.:.......:
Mouse    63 KPSAARRGAAQGAPLPASVVKKKRKKKKEKKKRLPSNEIKHWNHPHQLEEKEEEQEQVEKCEQEL 127

  Fly    69 GGGSGKSEATNGIDRPCDKAAITEFNDD-----EDEAKAATKIQAVFRGHKVRETMKKSETKTAT 128
            ...||:.|           ..:|.|.:.     |.|..||.|||::||||..||.:||.::....
Mouse   128 AKSSGREE-----------TPVTPFEESTEEEREQEEAAALKIQSLFRGHVAREEVKKMKSDKNE 181

  Fly   129 N 129
            |
Mouse   182 N 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
igl	NP_477060.1	Adgb_C_mid-like	<74..>129	CDD:412094	18/59 (31%)
		IQ motif	104..122	CDD:412094	10/17 (59%)
		Adgb_C_mid-like	<169..>209	CDD:412094
		IQ	169..185	CDD:197470
		IQ motif	172..189	CDD:412094
		globin helix A	196..209	CDD:412094
		IQ	216..235	CDD:197470
Spa17	XP_011240741.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832224
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_106874
Panther	1	1.100	-	-	LDO	PTHR10699
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8834
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.960