DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment igl and Gap43

DIOPT Version :9

Sequence 1:	NP_477060.1	Gene:	igl / 36681	FlyBaseID:	FBgn0013467	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_032109.1	Gene:	Gap43 / 14432	MGIID:	95639	Length:	227	Species:	Mus musculus

Alignment Length:	171	Identity:	51/171 - (29%)
Similarity:	69/171 - (40%)	Gaps:	40/171 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 EFNDD-----------EDEA-KAATKIQAVFRGHKVRETMK----------KSETKTATNNGSAA 134
            |.||:           ||:| ||||||||.||||..|:.:|          ::|.|...:...|.
Mouse    12 EKNDEDQKIEQDGVKPEDKAHKAATKIQASFRGHITRKKLKGEKKGDAPAAEAEAKEKDDAPVAD 76

  Fly   135 G---------AAPSAAAAEAAASAEPTKA-ELEAEFDPNDKDLCHAALKIQSTFRGHLARKLVNK 189
            |         |...||.|.:..:.||:|| :..:|....:.|...:..|..|. ....|.|....
Mouse    77 GVEKKEGDGSATTDAAPATSPKAEEPSKAGDAPSEEKKGEGDAAPSEEKAGSA-ETESAAKATTD 140

  Fly   190 DAP----EDEDIQEITKKV---AEELDIDLTDPELNKAATK 223
            ::|    ||...:|..|:.   |...|...|.|....||||
Mouse   141 NSPSSKAEDGPAKEEPKQADVPAAVTDAAATTPAAEDAATK 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
igl	NP_477060.1	Adgb_C_mid-like	<74..>129	CDD:412094	22/58 (38%)
		IQ motif	104..122	CDD:412094	11/27 (41%)
		Adgb_C_mid-like	<169..>209	CDD:412094	10/46 (22%)
		IQ	169..185	CDD:197470	3/15 (20%)
		IQ motif	172..189	CDD:412094	4/16 (25%)
		globin helix A	196..209	CDD:412094	3/15 (20%)
		IQ	216..235	CDD:197470	4/8 (50%)
Gap43	NP_032109.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..227		51/171 (30%)
		IQ	30..52	CDD:197470	14/21 (67%)
		Neuromodulin	73..227	CDD:369001	29/110 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10699
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010