DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8089 and zgc:175107

DIOPT Version :9

Sequence 1:	NP_611014.1	Gene:	CG8089 / 36679	FlyBaseID:	FBgn0033993	Length:	624	Species:	Drosophila melanogaster
Sequence 2:	NP_001107104.1	Gene:	zgc:175107 / 794317	ZFINID:	ZDB-GENE-080220-38	Length:	333	Species:	Danio rerio

Alignment Length:	350	Identity:	84/350 - (24%)
Similarity:	135/350 - (38%)	Gaps:	81/350 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   225 RELHENKRYKRLLENQKSQEEKELELSLNKVEDILVPVAEDLQSYFKDES--------------- 274
            :|..|:.:.:.....:....:|:.:|:..|||.......|:...|.|.:|
Zfish     5 KEESEDLKIEHTFTVKHEDRDKQTDLTAPKVERQETNELEERNQYDKRDSAIGEKSTHTQDASLL 69

  Fly   275 KHPIQKRKTSSLSKCPSCAQNYGFSFSHQLHMVKHRRERLYTNFPFHCSFCNRSFLTRKFLRKHQ 339
            |.| |..::|....|..|.:::|...:.::|...|..|:     ||.|..|.:||..::.|:.|
Zfish    70 KRP-QSAESSGYYICGECNKSFGLKQNLEVHKRTHTGEK-----PFSCQQCGKSFSQKQNLKVH- 127

  Fly   340 QRVRTFSTLLYRPFKCPHCTWRFQLKSALDSHV---------------------------LRIHE 377
            .||.|..    :||.||.|...|..|..|.:||                           :|||.
Zfish   128 MRVHTGE----KPFSCPFCGQNFTHKGNLKTHVRNHTGESAFICNLCGKSFSRKESLNTHMRIHS 188

  Fly   378 RRKP-----C---LICKLPTSRLCC-----SAHTSKECNRAMQKYRDKMRPLREPPKGGCRKQPT 429
            ..||     |   ..||:   .|.|     |..:|..|:...|.:.|. ..||........::|.
Zfish   189 GEKPFGCAQCGKTFRCKV---NLNCHMRIHSRESSFICHHCEQSFGDS-DELRSHVNTHVGEKPF 249

  Fly   430 PVCKICNRKFTRKFFLEEHMNKAHLNKRNFTCEICGANFYSQGTMQTHRKAVHLLVHT----VQC 490
             :|..|.:..:.|..||.| ::.|..:|.|.|..||.:|..:|.:.     :|:.|||    ..|
Zfish   250 -MCLHCGKSCSNKAVLEVH-SRIHTGERPFVCPQCGKSFTLRGNLN-----IHIRVHTGEKPFNC 307

  Fly   491 EVCDLTIKSKGNYRRHCKSQSHKDN 515
            ..|:.:.....:.:||.:|...|::
Zfish   308 VHCEKSFTYHTDLKRHLQSPCEKNS 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8089	NP_611014.1	C2H2 Zn finger	289..309	CDD:275368	4/19 (21%)
		C2H2 Zn finger	322..343	CDD:275368	7/20 (35%)
		C2H2 Zn finger	355..376	CDD:275368	9/47 (19%)
		C2H2 Zn finger	432..453	CDD:275368	6/20 (30%)
		C2H2 Zn finger	461..486	CDD:275368	6/24 (25%)
		C2H2 Zn finger	490..506	CDD:275368	2/15 (13%)
zgc:175107	NP_001107104.1	C2H2 Zn finger	83..103	CDD:275368	4/19 (21%)
		zf-H2C2_2	95..120	CDD:290200	9/29 (31%)
		COG5048	<107..286	CDD:227381	51/194 (26%)
		C2H2 Zn finger	111..131	CDD:275368	7/20 (35%)
		zf-H2C2_2	123..148	CDD:290200	11/29 (38%)
		C2H2 Zn finger	139..159	CDD:275368	8/19 (42%)
		zf-C2H2	165..187	CDD:278523	1/21 (5%)
		C2H2 Zn finger	167..187	CDD:275368	1/19 (5%)
		C2H2 Zn finger	195..215	CDD:275368	5/22 (23%)
		C2H2 Zn finger	223..243	CDD:275368	5/20 (25%)
		C2H2 Zn finger	251..271	CDD:275368	6/20 (30%)
		zf-H2C2_2	264..287	CDD:290200	9/23 (39%)
		C2H2 Zn finger	279..299	CDD:275368	6/24 (25%)
		zf-H2C2_2	291..316	CDD:290200	6/29 (21%)
		C2H2 Zn finger	307..324	CDD:275368	3/16 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24406
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100