DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8089 and Zfp276

DIOPT Version :9

Sequence 1:	NP_611014.1	Gene:	CG8089 / 36679	FlyBaseID:	FBgn0033993	Length:	624	Species:	Drosophila melanogaster
Sequence 2:	XP_006531290.1	Gene:	Zfp276 / 57247	MGIID:	1888495	Length:	669	Species:	Mus musculus

Alignment Length:	287	Identity:	62/287 - (21%)
Similarity:	101/287 - (35%)	Gaps:	62/287 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   242 SQEEKELELSLNKVEDILVPVAEDLQSYFKDESKHPIQKRKTSSLSKCPSCAQNYGFSFSHQLHM 306
            |::|.:.:.:....::...|..|...|..|.|.:. .::.:...:.|.|.....:       ...
Mouse   366 SEDESDKKQTPQSSDESFEPYPEKKVSGKKSEGRE-AKRPEEPKIRKKPGPKPGW-------KKK 422

  Fly   307 VKHRRERLYTNFPFHCSFCNRSFL----TRKFLRKHQQRVRTFSTLLYRPFKCPH--CTWRFQLK 365
            ::..||.|.|.:......|...:.    .:|.:::|.:.||.      ||  |||  |...|.:.
Mouse   423 LRCEREELPTIYKCPYQGCTAVYRGADGMKKHIKEHHEEVRE------RP--CPHPGCNKVFMID 479

  Fly   366 SALDSHVLRIHERRKPCLICKLPTS------RLCCSAHTSKECNR-AMQKYRDKMRP-------- 415
            ..|..||..||...:.|:....|:|      ....:|||:....| |:.......||
Mouse   480 RYLQRHVKLIHTGPRCCVKQWSPSSPGADWASAVAAAHTALLLQRSAITSVTSAGRPSSSGSTFS 544

  Fly   416 -----LREPPKGGCRK----------------QPTPV-CKICNRKFTRKFFLEEHMNKAHL-NKR 457
                 .|||  ..|.|                .|.|. |::|..:..::..|:.||.|... .:.
Mouse   545 STRCATREP--SHCSKCGLGTACDWDKCSLPHLPLPSRCEVCGFQCRQRASLKYHMTKHKAETEL 607

  Fly   458 NFTCEICGANFYSQGTMQTHRKAVHLL 484
            :|.|:.||..|.....:..|...||.|
Mouse   608 DFACDQCGRRFEKAHNLNVHMSMVHPL 634

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8089	NP_611014.1	C2H2 Zn finger	289..309	CDD:275368	1/19 (5%)
		C2H2 Zn finger	322..343	CDD:275368	3/24 (13%)
		C2H2 Zn finger	355..376	CDD:275368	8/22 (36%)
		C2H2 Zn finger	432..453	CDD:275368	6/20 (30%)
		C2H2 Zn finger	461..486	CDD:275368	8/24 (33%)
		C2H2 Zn finger	490..506	CDD:275368
Zfp276	XP_006531290.1	zf-AD	80..156	CDD:214871
		SFP1	<321..476	CDD:227516	24/125 (19%)
		C2H2 Zn finger	581..601	CDD:275368	5/19 (26%)
		C2H2 Zn finger	611..632	CDD:275368	5/20 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24406
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100