DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8089 and Sry-delta

DIOPT Version :9

Sequence 1:	NP_611014.1	Gene:	CG8089 / 36679	FlyBaseID:	FBgn0033993	Length:	624	Species:	Drosophila melanogaster
Sequence 2:	NP_524581.1	Gene:	Sry-delta / 43572	FlyBaseID:	FBgn0003512	Length:	433	Species:	Drosophila melanogaster

Alignment Length:	338	Identity:	69/338 - (20%)
Similarity:	109/338 - (32%)	Gaps:	126/338 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   237 LENQKSQEEKELELSLNKV----------------EDILVPVAEDLQSYFKDESKHPIQKRKTSS 285
            :|..|.|||.:.|:....|                ||:.|..:|.|.....|....|.:||..
  Fly   131 VELVKDQEESDTEIKREFVDEEEEEDDDDDDEFICEDVDVGDSEALYGKSSDGEDRPTKKRVK-- 193

  Fly   286 LSKCPSCAQNYGFSFSHQLH-----------------MVKHRRERLYTNFPFH-------CSFCN 326
             .:|.:|.:.|...:..|.|                 :::...|.|..:...|       |.:|.
  Fly   194 -QECTTCGKVYNSWYQLQKHISEEHSKQPNHICPICGVIRRDEEYLELHMNLHEGKTEKQCRYCP 257

  Fly   327 RSFL----TRKFLRKHQQRVRTFSTLLYRPFKCPHCTWRFQLKSALDSHVLRIHERRKP--CLIC 385
            :||.    |.:.:|.|..:         :.::|..|..||...:.|.:|.||......|  |.||
  Fly   258 KSFSRPVNTLRHMRMHWDK---------KKYQCEKCGLRFSQDNLLYNHRLRHEAEENPIICSIC 313

  Fly   386 KLP-TSRLCCSAHT--SKECNRAMQKYRDKMRPLREPPKGGCRKQPTPVCKICNRKFTRKFFLEE 447
            .:. .||...:.||  .|| ||                       |...|.:|.:.||.::.|:.
  Fly   314 NVSFKSRKTFNHHTLIHKE-NR-----------------------PRHYCSVCPKSFTERYTLKM 354

  Fly   448 HMNKAH----------------------------------------LNKRNFTCEICGANFYSQG 472
            || |.|                                        .::.:..|.||..||.::.
  Fly   355 HM-KTHEGDVVYGVREEAPADEQQVVEELHVDVDESEAAVTVIMSDNDENSGFCLICNTNFENKK 418

  Fly   473 TMQTHRKAVHLLV 485
            .::.|.:..|.:|
  Fly   419 ELEHHLQFDHDVV 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8089	NP_611014.1	C2H2 Zn finger	289..309	CDD:275368	5/36 (14%)
		C2H2 Zn finger	322..343	CDD:275368	7/24 (29%)
		C2H2 Zn finger	355..376	CDD:275368	8/20 (40%)
		C2H2 Zn finger	432..453	CDD:275368	8/20 (40%)
		C2H2 Zn finger	461..486	CDD:275368	8/25 (32%)
		C2H2 Zn finger	490..506	CDD:275368
Sry-delta	NP_524581.1	COG5048	<205..360	CDD:227381	41/188 (22%)
		C2H2 Zn finger	225..245	CDD:275368	2/19 (11%)
		C2H2 Zn finger	253..273	CDD:275368	6/19 (32%)
		C2H2 Zn finger	281..301	CDD:275368	7/19 (37%)
		C2H2 Zn finger	310..327	CDD:275370	5/16 (31%)
		zf-C2H2	337..359	CDD:278523	8/22 (36%)
		C2H2 Zn finger	339..359	CDD:275368	8/20 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455445
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930