DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8089 and si:dkeyp-2e4.2

DIOPT Version :9

Sequence 1:	NP_611014.1	Gene:	CG8089 / 36679	FlyBaseID:	FBgn0033993	Length:	624	Species:	Drosophila melanogaster
Sequence 2:	NP_001122042.1	Gene:	si:dkeyp-2e4.2 / 100149164	ZFINID:	ZDB-GENE-030131-9307	Length:	251	Species:	Danio rerio

Alignment Length:	278	Identity:	64/278 - (23%)
Similarity:	114/278 - (41%)	Gaps:	68/278 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   234 KRLLENQKS-QEEKELELSLNKVEDILVPVAEDLQSYFKDESKHPIQKRKTSSLSK--------- 288
            |.:::|::| |.:.|.:.:.|.||.:::...|...:.|....|:.::..:||..|.
Zfish     2 KPVIKNEESLQGDPESKSTNNDVETLVLSKTEGSAALFCRRLKYRVKTDQTSDQSSSDTDTEDEL 66

  Fly   289 -------------CPSCAQNYGFSFSHQLHMVKHRRERLYT-NFPFHCSFCNRSFLTRKFLRKH- 338
                         |..|...:|.:.|    ||:|.  |::| ..|:.|..|.:.|..:.:|::|
Zfish    67 PISTSPTPGEDLICKLCGSEFGSNIS----MVRHM--RIHTGETPYICEVCGKGFKRQGWLKEHF 125

  Fly   339 -----QQRVRTFSTLLYRPFKCPHCTWRFQLKSALDSHVLRIHERRKP--CLICKLPTSRLCCSA 396
                 .:|.|.      :...|..|..:|...:||.|| |..|...:|  |:
Zfish   126 RVHTGNKRKRE------KRLSCDQCEMKFNSSTALRSH-LNKHRGERPFACV------------- 170

  Fly   397 HTSKECNRAMQKYRDKMRPLREPPKGGCRKQPTPVCKICNRKFTRKFFLEEHMNKAHLNKRNFTC 461
                :|::......|..:.||:     |.......|.:|..:|||:..|::|| :.|..:|.::|
Zfish   171 ----QCDKTYFNQHDLNQHLRD-----CHSDKKHGCYLCGNEFTRQSSLQKHM-RIHTGERPYSC 225

  Fly   462 EICGANFYSQGTMQTHRK 479
            ..||..|..:.:|:.|.|
Zfish   226 PHCGKTFSYKHSMKMHVK 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8089	NP_611014.1	C2H2 Zn finger	289..309	CDD:275368	6/19 (32%)
		C2H2 Zn finger	322..343	CDD:275368	6/26 (23%)
		C2H2 Zn finger	355..376	CDD:275368	8/20 (40%)
		C2H2 Zn finger	432..453	CDD:275368	8/20 (40%)
		C2H2 Zn finger	461..486	CDD:275368	7/19 (37%)
		C2H2 Zn finger	490..506	CDD:275368
si:dkeyp-2e4.2	NP_001122042.1	C2H2 Zn finger	80..100	CDD:275368	8/25 (32%)
		zf-H2C2_2	92..117	CDD:290200	10/30 (33%)
		C2H2 Zn finger	108..128	CDD:275368	5/19 (26%)
		C2H2 Zn finger	141..161	CDD:275368	8/20 (40%)
		C2H2 Zn finger	169..217	CDD:275368	14/70 (20%)
		zf-H2C2_2	209..234	CDD:290200	9/25 (36%)
		C2H2 Zn finger	225..243	CDD:275368	6/17 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24406
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100