Protein Alignment chn and Zfp518b

DIOPT Version :10

• Sequence 1: NP_001246331.1
• Gene: chn / 36678
• FlyBaseID: FBgn0015371
• Length: 1286
• Species: Drosophila melanogaster
• Sequence 2: NP_001419754.1
• Gene: Zfp518b / 498390
• RGDID: 1564150
• Length: 1077
• Species: Rattus norvegicus
• Alignment Length: 1022
• Identity: 189/1022 - (18%)
• Similarity: 305/1022 - (29%)
• Gaps: 390/1022 - (38%)

  Fly   493 EKRFTCCYCPWSGADKWGLKRHLNTHTK--PFVCLLCDYKAARSERLATHVLKVHNKRACSKCSY 555
            |.:|.|.:|.:....|...:|||..||.  |:.|..|||.|.|::.:..|..:|| :||.:|..:
  Rat   162 EIKFICSHCSYISYTKGEFQRHLVKHTGIFPYRCEYCDYGAIRNDYIVKHRRRVH-ERAGAKRPF 225

  Fly   556 ---------------------------------LADTQEEYQAHMSDVHPHD------------- 574
                                             |:|....:..|.|....|:
  Rat   226 KTVAKLEPKRTNISKQSMELSKAPSPRAAFQNKLSDQLSRFSLHASKDKTHNMMLLPELKKYQKD 290

  Fly   575 -------------NRPARSGNGNQSGGSSSGNSNGNGGG-------------------------- 600
                         ...:..||.|......|.:......|
  Rat   291 VVCIPNKVTLCEPREVSLLGNKNVEVEVLSPSKEPVQPGLPLTVMAPSELVVPTNCLAQLMDVKV 355

  Fly   601 -NGNNNANAGGHSQNLNVLRTIGNSLVANNQLNTYAGNAFGSSSGNVGNANGGGGAVTIYTTTTN 664
             ||         :|.| ||:..  .|..|::|.|..|:  |..|.......|.||...:.:|..:
  Rat   356 VNG---------TQQL-VLKLF--PLEENSRLETSRGD--GGVSECTTTEKGSGGQTKVLSTEAS 406

  Fly   665 EGVAGGGGGGGGGISGNISGGGPLQEIIVNPSSMVGWRLSAN----------------------- 706
            ..:|..|.      :|...|...|..::......|.|..|.|
  Rat   407 RSLAMEGN------AGEFVGLDRLHSLVQKQLKNVKWVKSCNFFMPNSGIHSHQDSFLGPDTIKD 465

  Fly   707 ----GSLIPPHDLLTGGL---------------PNAATQKRGSERLFQYLEAEGSDPEDYARLLK 752
                .||.||..|.:..:               |.|...:..::....:.|.......|..:||.
  Rat   466 LQKSHSLCPPRALPSASVKSHSPASVQSSVSYGPGATVSRFLTKAAAAFAEDGRGSRSDSQQLLP 530

  Fly   753 MDAISRNTASVAQDFHKAGGVHELKIPANHQLLFNNKLPSQWTTREAAALLYS--------LSNM 809
            :.::|...:     |....|:    :|     |..|.|.::..|.....::.|        :.:.
  Rat   531 LASLSSKVS-----FSGEKGL----LP-----LGENDLEARNRTSRPETVVSSDRKLEDKPMESK 581

  Fly   810 GGGSASSVSGSQRQKFGMRARQHSTGEDDENT-----------PSSASSSSFSG----DEFNMSA 859
            ..||.|.||..|::::   ...:..|||...:           .|..:.::|.|    ..|::|:
  Rat   582 AVGSTSQVSSVQKKEY---LHINFAGEDKTRSQQPGGRPVLPKTSETAGNAFEGPIISSVFSLSS 643

  Fly   860 TSPLKLSRHAIKLEKMDEMDAKDMGPTKAMMATAFLEAANYEQTAIELLASKRKIKVENDNDEDQ 924
            .|           |.:.|....:...||.              .:||||  :|||
  Rat   644 GS-----------ENVPEGIKWNSSTTKI--------------KSIELL--RRKI---------- 671

  Fly   925 ENQQHQPHQQHHSQQQQQQRLQLIKSSPAYKLNNNNNNNSNNNNYYKDKTSHRNAVHHHRQDDKE 989
                                .|||:|.                    .|.|..:|....|:...:
  Rat   672 --------------------AQLIESC--------------------GKPSSLSAGSPQRRPIGQ 696

  Fly   990 NNKTKSPGT-AAVSVAAAAATSP-PSI---SGPSNQ---------------TPFLTQMEYQNLNR 1034
            ..|..|..| .|:...:.:.|.| ||:   ..|.|:               .||::..:.:..:|
  Rat   697 APKLTSKATPKAIQEMSGSLTGPGPSVGPLQKPQNEDSITGSGQHAPQQMCPPFVSANDGKTESR 761

  Fly  1035 IGTQF---------QNYVKDIINKYYAA-------ETPLML----AAAAAALPTATT----TGQQ 1075
            :..:.         :..|..::|....|       :||:.:    |..|..||....    :|.|
  Rat   762 VTRKTPVATPVLIPKGAVLRVLNSSEDARIIEATCDTPVSIPCSEAQLAGTLPFCPVKQPGSGSQ 826

  Fly  1076 QQP-ELDIENLSPSKRRRLLSETEEYIEYLRNKEDITLTIAPK----VQPPAPVTSLLKRQ---- 1131
            ..| .....:||||....|..::        .|||...::.||    |....|.:|...||
  Rat   827 LLPCRSGPADLSPSLETSLRPKS--------RKEDPICSVTPKKIIPVYSTVPGSSDSSRQGRPV 883

  Fly  1132 ---LDLSTPRRSPKKAAPAHSNSASNASR----KSLNQLATLLPLLADAASQQEYLAAP------ 1183
               |.:|..:.....:|...:...:|.||    .|..|:|..|.|:  ||...:.:..|
  Rat   884 SRNLTVSKNKTKQVSSAKKKNKMQANPSRYFKDPSFFQVARQLRLI--AAKPDQLIKCPRRNQPV 946

  Fly  1184 -----------------------------LDFSKKSSSRKQAQPKKIRLTPEAVVTLLRDKYLNR 1219
                                         :..|:::..:...:...:|||.:.|..      .|.
  Rat   947 IVLNHPDVDSPEVTNVMKVINKYKGNVLKVVLSERTRCQLGVRRYHMRLTYQNVAE------TNH 1005

  Fly  1220 MVRQRLGCLKCNQLRKNSSISFNYHTLGSL------ALHKYWRHGRL 1260
            |.||.:..:|..::.||     ||..:|||      .:.|.|..|||
  Rat  1006 MKRQMMLKMKLKKVHKN-----NYQVVGSLPDDPAQCVFKCWFCGRL 1047

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chn	NP_001246331.1	C2H2 Zn finger	307..327	CDD:275368
		C2H2 Zn finger	335..356	CDD:275368
		C2H2 Zn finger	498..518	CDD:275368	6/19 (32%)
		C2H2 Zn finger	524..545	CDD:275368	7/20 (35%)
Zfp518b	NP_001419754.1	C2H2 Zn finger	140..160	CDD:275368
		zf-H2C2_5	167..189	CDD:404746	7/21 (33%)
		C2H2 Zn finger	167..187	CDD:275368	6/19 (32%)
		C2H2 Zn finger	195..216	CDD:275368	7/20 (35%)