Protein Alignment chn and Zfp518a

DIOPT Version :10

• Sequence 1: NP_001246331.1
• Gene: chn / 36678
• FlyBaseID: FBgn0015371
• Length: 1286
• Species: Drosophila melanogaster
• Sequence 2: NP_001025209.1
• Gene: Zfp518a / 309478
• RGDID: 1305314
• Length: 1478
• Species: Rattus norvegicus
• Alignment Length: 1077
• Identity: 201/1077 - (18%)
• Similarity: 333/1077 - (30%)
• Gaps: 339/1077 - (31%)

  Fly   255 QNLAQSTPTSAPSNSSGGSTSSSGGGGGRKKAAQAAAAAAAANGVHIQK--RYACTHC----PYS 313
            :.|.||.|.:|..:.|..:.|.:.|...|.::.:|...|    |....|  .:.|:.|    .||
  Rat    73 RKLFQSKPQTARKSVSVRTVSCAKGCAQRCESERAEDEA----GKMCAKILNFTCSKCQDRTQYS 133

  Fly   314 TDRRDLYTRHENIHKDEKP-FQCYACLKQFNRADHVKKHFLRMHRELQYDINKTRRHVSAGSGSS 377
            .:  ||....|..|..|.| |.|..|  .|:.:|.   ...:.||       ||.|
  Rat   134 PN--DLQKHFEMWHHGELPSFPCEMC--SFSASDF---QIFKQHR-------KTHR--------- 175

  Fly   378 GSGSSGSGSHHSGGRGNVTINSAGVNIDNAF--LEAQRHPTSSSMSIVETIEAVASATDMPLAQL 440
                            |..:.....|.:.::  |:..:|.||
  Rat   176 ----------------NTFVKCDICNSERSYTLLDLTKHFTS----------------------- 201

  Fly   441 KQEKMDDGAGVVLPLHVGVMQQPVASSSSGSSGSHGGNGN------------GGSGSGLLKPKRE 493
                                             .|..|||            .|:....:...:|
  Rat   202 ---------------------------------KHCVNGNFQCEECRFFTQDVGTFVQHIHRHKE 233

  Fly   494 KRFTCCYCPWSGADKWGLKRHLNTH--TKPFVCLLCDYKAARSERLATHVLKVHNKRACSKCSYL 556
            ..:.|..|......|..|::||..|  |.||.|..|.|.|...::|..||:.:|.:..     |.
  Rat   234 VHYKCGKCHHLCFTKGELQKHLRVHSGTLPFTCHYCSYGAIHKDQLVRHVITLHKEHL-----YA 293

  Fly   557 ADTQEEYQAHMSDVHPHDNRPARSGNG------------NQSGGSSSGNSNGNGGGNGNNNANAG 609
            .:..|..|        :|.|.|::..|            .::.......::||....|.|
  Rat   294 KEKLERDQ--------YDKRVAKTTTGLKLILKRYKIGPTKTFWKRKTIASGNDESIGKN----- 345

  Fly   610 GHSQNLNVL-RTIGNSL-VANNQLNTYAGNAFGSSSGNVGNANGGGGAVTIYTTTTNEGVAGGGG 672
              :|..|:: :|...|. .:..|||...|.......|:....:|...|..:.|...|:  |..|.
  Rat   346 --AQAFNIVSKTQTKSEDQSQEQLNEEKGGRQHCEDGDKPIESGSEKATVLSTGQCNK--ADEGA 406

  Fly   673 GGGGGISGNISGGGPLQEIIVN-----PSS---------MVGWRLSANGSLIPPHDLLTGGLPNA 723
            .....:...:.  ||...::.|     |::         ||..|......|:|.:..:   ||:.
  Rat   407 SAPSSVLSAVQ--GPTVLLVRNNKITIPANYSAKFMGFKMVDGRQHIVIKLLPANKQI---LPSP 466

  Fly   724 ATQKRGSERLFQYLEAEGSDPEDYARLLKMDAISRNTASVAQDFHKAGGVHELKIPANHQLLFNN 788
            |.|....:.....|..:..|...:|..|        ||....||.||..:.          ..:.
  Rat   467 ALQPNTEKESTANLPPQAMDNTGFATGL--------TAMNDTDFVKAAPLS----------CSSP 513

  Fly   789 KLPSQWTTREAAALLYSLSNMGGGSASSVSGSQRQKFGMRARQHSTGEDDENTPSSASSSSFSGD 853
            :||.:..:.:..|.:...:||                 ::....|.......|||.:.:|
  Rat   514 ELPRKVISEKETAFISEKNNM-----------------LQMVDDSKSVTSLPTPSESVTS----- 556

  Fly   854 EFNMSATSPLKLSRHAIKLEKMDEMDAKDMGPTKAMMATAFLEAANYEQTAIELLASKRKIKVEN 918
                        .|...|:|..|.:|..:...|               |:..:|:.:       :
  Rat   557 ------------VRLTTKVEARDNVDLWENPST---------------QSHPDLIGT-------S 587

  Fly   919 DNDEDQENQQHQPHQ----QHHSQQQQQQRLQL-IKSSPAYKLNNNN----NNNSNNNNYYKDKT 974
            .|..|:.|...:|:.    ..|:........:| .:||..::.:|..    :|.|..||  |.:.
  Rat   588 INSPDKVNLTIRPNAYSCGDMHNYCINYVNSELPAESSNCFEFSNQGSLPFHNYSKVNN--KRRR 650

  Fly   975 SHRNAVHHHRQDDKENNKTKSPGTAAVSVAAAAATSP------------PSISGPSNQTPFLTQM 1027
            ..|.||..:.|.: .:|||    ....|.:.:..|||            .|||..|......|::
  Rat   651 FSRGAVCENLQRE-SSNKT----VTQQSTSDSDTTSPLRKESSNSDSLLASISPLSGTLKIKTEI 710

  Fly  1028 -------EYQNLNRIGTQFQNYVKDIINKYYAAETPLMLAAAAAALPTATTTGQQQQPELDIENL 1085
                   |.||.|. .:.|.|..::::|.....:...:..|.:..:|..|:....|..:  ....
  Rat   711 EEPCDLEETQNFNE-QSLFTNENQNLLNMTEEPKWDDIPCAGSPMMPRITSVFSLQSEQ--ASEF 772

  Fly  1086 SPSKRRRLLSETEEYIEYLRNKEDI--TLTIAPKVQPPAPVTSLLKRQLD--------------L 1134
            .|.:..:||.:|      |:.:.||  .....|....|......||:..:              :
  Rat   773 LPPEVNQLLQDT------LKPRSDIKEDSNNIPSKNLPLDCDQTLKKSKEEVIKSSKDFQMQDII 831

  Fly  1135 STPRRSPKKAAPAHS-NSASNASRK----------------SLNQLATLLPLLADAASQQEYL-- 1180
            |.|..|.....||:. |...|...|                .:..:.|||...:||...|:.:
  Rat   832 SVPSASVGVNVPANDLNLKCNGQEKQALSVLQDVRDPGVTTKIPSIITLLKTQSDAIITQQLVKD 896

  Fly  1181 --------AAPLDFSKKSSSRKQAQPKKIRLTPEAVV 1209
                    :.|:.......:.:|..|..:: ||:..:
  Rat   897 KLRTTTQHSGPVYVQNPLLTSEQKNPVFVQ-TPKGFI 932

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chn	NP_001246331.1	C2H2 Zn finger	307..327	CDD:275368	7/23 (30%)
		C2H2 Zn finger	335..356	CDD:275368	4/20 (20%)
		C2H2 Zn finger	498..518	CDD:275368	6/19 (32%)
		C2H2 Zn finger	524..545	CDD:275368	7/20 (35%)
Zfp518a	NP_001025209.1	C2H2 Zn finger	181..203	CDD:275368	5/77 (6%)
		C2H2 Zn finger	211..231	CDD:275368	1/19 (5%)
		C2H2 Zn finger	238..258	CDD:275368	6/19 (32%)
		zf-H2C2_2	250..271	CDD:463886	9/20 (45%)
		C2H2 Zn finger	266..283	CDD:275368	5/16 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	355..394		9/38 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	464..484		4/19 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	656..694		9/42 (21%)