Protein Alignment pcs and rei-2

DIOPT Version :9

• Sequence 1: NP_611010.4
• Gene: pcs / 36674
• FlyBaseID: FBgn0033988
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_508206.2
• Gene: rei-2 / 180461
• WormBaseID: WBGene00019365
• Length: 431
• Species: Caenorhabditis elegans
• Alignment Length: 409
• Identity: 115/409 - (28%)
• Similarity: 192/409 - (46%)
• Gaps: 43/409 - (10%)

  Fly     5 EDGE--LDPQ----IQIELENLNSATDEINKLEIELEEANSTFRILLNESTRRLKVSSKKLGNCI 63
            |||.  |:.:    |..|||.||.:||.|||:|::|:.|.:.||....:.:.:||..||:..:.|
 Worm    25 EDGHPPLETRHLNMIHEELEKLNISTDVINKMEVQLDLARADFRETQVQWSEKLKELSKQYSSQI 89

  Fly    64 EKARPYYEALDKAREAQIECQKAAVKFQRANEIHAAAKETVALAEQRFMSNSHEWQFDNAWQEML 128
            .||||:||...|.|..:.|.||||.:|:||..|...||:.|:|.::   |.|.:........|:|
 Worm    90 AKARPFYELKIKERSLREESQKAAERFERATSILGIAKQQVSLTQE---SLSRQTSVLPECLEVL 151

  Fly   129 NHATQKVMDAETQKADCHAEHQRLTKLFNAAEQKLQQLEDRFRRSINKSRPYFEEKQVCQDQLQT 193
            ||..|:|.:.|.::....:.|...........:|::.:|...|.:|.|||.|||::......|:.
 Worm   152 NHHIQRVREVEEERTAAESLHASKAHAMLHLAEKIRAMEKDNRYAIKKSRLYFEKRLEFTKILEA 216

  Fly   194 QKNRIQELQQQVAGAKSTYSTALRNLERISEDIHRQRGDFPTPPGPREPGVGAELNSPTSSALPS 258
            ||..|..|:.:|...|:.|:|:|||||||||.||.:|                     ::.:|.|
 Worm   217 QKATILCLEAEVRQKKNDYTTSLRNLERISERIHEER---------------------STGSLES 260

  Fly   259 LPDFQLELEKCDYPSIAGSQMSLGAKTPQAAAETEDEEDACDYDETGAGELRGVV--------DE 315
            ......|.:|.|:.|   |:...|...|.|.......||....|:.....:..::        ::
 Worm   261 AVSSDQEDQKSDFKS---SESLPGNPPPYAPTAPPPYEDKYIIDKDDDSIVLNMIKTEQEEEGEK 322

  Fly   316 RDLEALRQKVKILAVRPIEGGDGQQQNDVW--EHELKATVDKLDHLMMLKETAKRQQTNRLKSTE 378
            |:..:|...|.:||.:.|..|:..:::::.  .|..:|.:......:.|.:.:...:.:.|.|..
 Worm   323 RNSRSLGSGVILLAQQLIGNGNSTEKHNITPPRHGEEADISYHTRPVGLSDGSDNSEVSSLASFN 387

  Fly   379 QRPDSLGAEALKRHCDVVE 397
            ...|...::.|..|.::::
 Worm   388 IGDDDTVSKMLMSHSELIK 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pcs	NP_611010.4	SH3BP5	8..235	CDD:283045	84/232 (36%)
rei-2	NP_508206.2	SH3BP5	33..259	CDD:283045	83/249 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162249
Domainoid	1	1.000	132	1.000	Domainoid score	I3180
eggNOG	1	0.900	-	-		E1_KOG2008
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	135	1.000	Inparanoid score	I3147
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003963
OrthoInspector	1	1.000	-	-		mtm4787
orthoMCL	1	0.900	-	-		OOG6_104684
Panther	1	1.100	-	-	LDO	PTHR19423
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3845
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.820