DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pcs and sh3bp5l

DIOPT Version :9

Sequence 1:	NP_611010.4	Gene:	pcs / 36674	FlyBaseID:	FBgn0033988	Length:	477	Species:	Drosophila melanogaster
Sequence 2:	NP_001093720.1	Gene:	sh3bp5l / 100101740	XenbaseID:	XB-GENE-920564	Length:	373	Species:	Xenopus tropicalis

Alignment Length:	330	Identity:	136/330 - (41%)
Similarity:	185/330 - (56%)	Gaps:	43/330 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SAEDG-------ELDPQIQIELENLNSATDEINKLEIELEEANSTFRILLNESTRRLKVSSKKLG 60
            |:.||       ||||:||.|||.||.|::|||.||::|:||.:.:|.:|.||.|||...:.:||
Frog    44 SSNDGKKEEIEEELDPRIQEELERLNQASEEINLLELQLDEARTAYRRILTESARRLNGLATQLG 108

  Fly    61 NCIEKARPYYEALDKAREAQIECQKAAVKFQRANEIHAAAKETVALAEQRFMSNSHEWQFDNAWQ 125
            .||:||||||||...|:|||.:...||::::||..:||||:|.|.:|||...::.:  :.|..||
Frog   109 ACIDKARPYYEARRLAKEAQQDTHSAALRYERAVSMHAAAREMVFVAEQGVTADKN--RLDPTWQ 171

  Fly   126 EMLNHATQKVMDAETQKADCHAEHQRLTKLFNAAEQKLQQLEDRFRRSINKSRPYFEEKQVCQDQ 190
            |||||||.||.:||.::.....||||:|:..:.||.|:|.|:...:|.|.|||||||.|......
Frog   172 EMLNHATCKVNEAEEERLRSEFEHQRVTRQCHEAEAKVQTLQKSLKRFIIKSRPYFELKSQLNTI 236

  Fly   191 LQTQKNRIQELQQQVAGAKSTYSTALRNLERISEDIHRQRGDFPTPPGPREPGVGAELNSPTS-- 253
            |:..|:|:..|:..||.||..||..|||||:|||:||.:|.. .:....|.|.:|||  :|.|
Frog   237 LEEHKSRVTSLENSVAQAKLRYSGTLRNLEQISEEIHARRTQ-SSLLSQRAPPLGAE--APPSVK 298

  Fly   254 ----------SALPSLPDFQLELEKCDYPSIAGSQMSLGAKTPQAAAETEDEEDACDYD--ETGA 306
                      .:|.||.....:|:|.|                 :.....|..|....|  ||||
Frog   299 DGETGPPADTVSLLSLQTIASDLQKSD-----------------SVEHLRDLTDVTSLDGRETGA 346

  Fly   307 GELRG 311
            .|..|
Frog   347 VECGG 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pcs	NP_611010.4	SH3BP5	8..235	CDD:283045	111/226 (49%)
sh3bp5l	NP_001093720.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..53		3/8 (38%)
		SH3BP5	55..283	CDD:368365	111/230 (48%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	276..305		8/31 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	344..373		5/8 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D258813at33208
OrthoFinder	1	1.000	-	-		FOG0003963
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19423
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3845
SonicParanoid	1	1.000	-	-		X5780
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.050