Protein Alignment ckn and sash1b

DIOPT Version :10

• Sequence 1: NP_611009.1
• Gene: ckn / 36673
• FlyBaseID: FBgn0033987
• Length: 924
• Species: Drosophila melanogaster
• Sequence 2: XP_073784235.1
• Gene: sash1b / 566448
• ZFINID: ZDB-GENE-110228-1
• Length: 1157
• Species: Danio rerio
• Alignment Length: 793
• Identity: 138/793 - (17%)
• Similarity: 241/793 - (30%)
• Gaps: 315/793 - (39%)

  Fly   259 LIIDWLLEMKHEEYAQLFIAAGY-DLPTIARMTPEDLTAIGIKNPHHRERIKQRIDKLQ------ 316
            ::.:||..::..:|.:.|:..|| ||....::...||.|||:.:|||||::.:.:::|:
Zfish    14 IVYEWLKTLQLCQYVESFVDNGYDDLEVCKQIGNPDLDAIGVISPHHREKLLRAVERLRDEDKKV 78

  Fly   317 ------VLDNLPH-FVPG----------SIEEWL-------------QLLRLEEYIQPLLEQNYK 351
                  .|:.||| ..|.          |.:.|:             .:..||.:.:|::....|
Zfish    79 APALYFTLEPLPHGTYPNTSQISDCKQKSTKSWVNSTCDRPRIGFSSDITTLEIHKEPVVYPKLK 143

  Fly   352 TVRDVTQVTWEDLEDIGIVKLGHQKKILLAIKRVKDII-------SGKWNPGGANAYQQQEYQRK 409
            .                        ||::..|.|||.|       |.|....|..|...|||.
Zfish   144 L------------------------KIMIRDKLVKDGIDLSKMPYSYKDGSLGNIADLAQEYS-- 182

  Fly   410 PWQFNVPIPSTPSYVPTTRVSWDDTKIYATSSVLNSTAPSGSSCLNSSLANGDAYYCTGSNHECC 474
                        .|..|:.....|.........:...|.:|.:...:||.
Zfish   183 ------------EYYSTSYSEVCDRMEELRKRRVTQEAETGKAESTTSLQ--------------- 220

  Fly   475 SGNDVVLIKVRQPRGKS-------LESLEDIHDNST-----------RSHLTFSHYTTTDYGHFG 521
                 :.:::::..|.|       :|..:.:|.:|:           ::...:.::.....|.|.
Zfish   221 -----LRLEIQETLGLSSAVSTPEIERRQTMHKSSSEDGSAGRWDRKKNKSFWQNFRKAQKGSFR 280

  Fly   522 PPTTAAAAAAMAAAATLQQQHHHQQLLHQQQQ----QAAAARL--------LGNNAPGIGWRRSY 574
            .|........:|:..|:..:...|.::..:::    :.|.|||        ..|:|....|..
Zfish   281 TPPKGEDLGFVASEITMSDEERIQLMMMVKEKMITVEEALARLKEYETQNKQSNSADMTDWTE-- 343

  Fly   575 DDGDITPTNDATRELLYEQEGGGTLPRQQRGILQRAVLNTMPPLEHHHYMNAAAAAEYGAASGVE 639
                 ||:...|........      .|....|:.:|  |...|  |..:|:...
Zfish   344 -----TPSPSMTESSYCNSR------EQSEDELEESV--TFRRL--HKLVNSTRR---------- 383

  Fly   640 GGANYMGGSPLTGKKIAPEPPRRHCSIRNSRTLSGEGVPSGAAAQAHQQAAQQQQGQHMFYGHTA 704
                      :..|.|..:..::|.|   ...||.|..|||             :|..::.|
Zfish   384 ----------VRKKLIRIDEAKKHGS---KDMLSLEASPSG-------------EGVSLYSG--- 419

  Fly   705 QHWQQQQQQAGAGTGQQPIYANYATIQQTTAEIHCEKYHDSKSTSSIDSIDTIPFANE-NTGTIK 768
                              ::...|.:|:..               |:||:.|.|.::. :|.:..
Zfish   420 ------------------VHKREAGVQEQL---------------SLDSLSTSPSSSSLDTSSSG 451

  Fly   769 QRLL-------NRQELQG------------GGAGNNNVPGGG-------------------HPAH 795
            |||.       :.|.|:.            ||:|::.....|                   :||:
Zfish   452 QRLFRAFSKSCSAQGLEAPAGPTGQGSELDGGSGSSFSEADGELEPRMSRSVTDGEMRRALNPAN 516

  Fly   796 LH------------------SSSSS-------------SSSSSTNTIANIAHSFHSLKSS----- 824
            .|                  |||||             ||.|.|.:..::.....|:|.:
Zfish   517 YHGRTCSFGGFDLTSRSVYMSSSSSDPTNENSEISLRDSSRSPTPSRISLGKKVKSVKETMRKRI 581

  Fly   825 SSLHDATLARSESMGSTAS-------------------GGSALHLRSPTLDMSNAGGSTAEPASS 870
            |..:.::|:...|.....|                   |||...|||.....|:..|.|.....|
Zfish   582 SKKYSSSLSEQSSPSRAPSSPQSPHTDTDSLEKPKLKAGGSVESLRSSLSGQSSMSGQTVSTTDS 646

  Fly   871 PEAAVPTVAINNG 883
            ..:...:|...:|
Zfish   647 SASNRESVKSEDG 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ckn	NP_611009.1	SAM_caskin1,2_repeat1	254..319	CDD:188896	19/72 (26%)
		SAM_caskin1,2_repeat2	320..390	CDD:188897	17/100 (17%)
		Caskin-tail	<887..912	CDD:465209
sash1b	XP_073784235.1	None