DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ckn and sash3

DIOPT Version :9

Sequence 1:	NP_611009.1	Gene:	ckn / 36673	FlyBaseID:	FBgn0033987	Length:	924	Species:	Drosophila melanogaster
Sequence 2:	NP_001016498.1	Gene:	sash3 / 549252	XenbaseID:	XB-GENE-1016821	Length:	389	Species:	Xenopus tropicalis

Alignment Length:	368	Identity:	72/368 - (19%)
Similarity:	124/368 - (33%)	Gaps:	105/368 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 HHQNHQADDGISMSGSSIVSSPSLEEGGFNLPRETSVALRLKDEVGGTSTAAPTTGGPGGGGATV 133
            |.:..|........|.|..|||.:.|..|||..:..     :||.|.|:.....:.|.
Frog    16 HKKKLQRSSSFKDFGKSKPSSPVVSEKEFNLENDIP-----EDEAGVTADENKQSSGK------- 68

  Fly   134 VGAPPPGAGKPGVAMVPPPPVFCATLREPL---THKAAVYYHQQLALQEDQGIDLTQSPGRDSPG 195
                   ..|...|      |...|:...:   ..||..:             ::.:..|..||.
Frog    69 -------LSKKWRA------VISRTMNRKMGKEVMKAMAH-------------EIGEPTGPSSPI 107

  Fly   196 SSSGSAGSGSRHSTASLDSGRASSYLTGVSSSGASIRA------------------PLSSPRCSS 242
            |:.||.  ...|..:|.......|.::..:|||:.:.:                  |.:.|.|..
Frog   108 STDGSI--DGMHRKSSDPEENLHSPVSRQTSSGSEVFSPSFMINNRDSINLENLPPPYNGPFCGK 170

  Fly   243 V--------SSCSIGSVDRQRNDELIID---------W--LLEMKHEEYAQLFIAAGYDLPTIAR 288
            .        |.....|:..::.|  |||         |  :|..|...:..:::    ||.....
Frog   171 AKVHTDFIPSPYDGDSLKLKKGD--IIDIIEKPPVGTWTGMLRNKIGSFKFIYV----DLVPEET 229

  Fly   289 MTPEDLTAIGIKNPHHRERIKQRIDKLQVLDNLPHFVPGSIEEWLQLLRLEEYIQPLLEQNYKTV 353
            .||        |....|.:::.:..|           |.:::|.|:.:.::|:|..||...|:|:
Frog   230 ETP--------KKTKTRTKVRSKRQK-----------PKTVQELLERINMQEHIPTLLLNGYETI 275

  Fly   354 RDVTQVTWEDLEDIGIVKLGHQKKILLAIKRVKDIISGKWNPG 396
            .|...::...|.::.|....|:.|:|.|.:.:.|..:|....|
Frog   276 EDFKDLSENHLIELNITDPQHRVKLLTAAEFLLDYDTGSETEG 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ckn	NP_611009.1	SAM_caskin1,2_repeat1	254..319	CDD:188896	14/75 (19%)
		SAM	260..316	CDD:197735	13/66 (20%)
		SAM_caskin1,2_repeat2	320..390	CDD:188897	17/69 (25%)
		SAM	326..387	CDD:197735	16/60 (27%)
		Caskin-tail	<887..912	CDD:293238
sash3	NP_001016498.1	SLY	19..167	CDD:372142	34/187 (18%)
		SH3_SASH3	169..224	CDD:212901	9/60 (15%)
		SAM_SASH-like	247..306	CDD:188892	17/69 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910