Protein Alignment ckn and INPPL1

DIOPT Version :9

• Sequence 1: NP_611009.1
• Gene: ckn / 36673
• FlyBaseID: FBgn0033987
• Length: 924
• Species: Drosophila melanogaster
• Sequence 2: XP_024304269.1
• Gene: INPPL1 / 3636
• HGNCID: 6080
• Length: 1324
• Species: Homo sapiens
• Alignment Length: 400
• Identity: 81/400 - (20%)
• Similarity: 122/400 - (30%)
• Gaps: 134/400 - (33%)

  Fly     5 LKPH-ASTAQAKKVQPPTIPGDSPQDLHLYQQPQQLHHHHHQHPNHHHPHHQP-----------S 57
            |||. |...:.....||....::|....|...|.||     ..|....|...|           :
Human  1027 LKPEGAPEPEGVAAPPPKNSFNNPAYYVLEGVPHQL-----LPPEPPSPARAPVPSATKNKVAIT 1086

  Fly    58 IPLYRLSGPLRHHQNHQADDGISMSGSSIVSSPSLEEGGFNLPRETSVALRLKDEVGGTSTAAPT 122
            :|..:|.    ||::.:..:|          |.|.||.|..||........|.|.......:...
Human  1087 VPAPQLG----HHRHPRVGEG----------SSSDEESGGTLPPPDFPPPPLPDSAIFLPPSLDP 1137

  Fly   123 TGGP---GGGGATVVGAPPPGAGKPGVAMVPPPPVFCATLREPLTHKAAVYYHQQLALQEDQGID 184
            ..||   |.|||...|.|||.|.       |.||:
Human  1138 LPGPVVRGRGGAEARGPPPPKAH-------PRPPL------------------------------ 1165

  Fly   185 LTQSPGRDSPGSS-SGSAGSGSRHSTASLDSGRASSYLTGVSSSGASIRAPLSSPRCSSVSSCSI 248
                |...||.|: .|...||...|.:.|...:..|.: ..:.:|.:..|.|..|
Human  1166 ----PPGPSPASTFLGEVASGDDRSCSVLQMAKTLSEV-DYAPAGPARSALLPGP---------- 1215

  Fly   249 GSVDRQRNDELIIDWLLEMKHEEYAQLFIAAGYDLPTIARMTPEDL-TAIGIKNPHHRERIKQRI 312
                            ||::.                 .|..|.|. ..:....|..||.|::
Human  1216 ----------------LELQP-----------------PRGLPSDYGRPLSFPPPRIRESIQE-- 1245

  Fly   313 DKLQVLDNLPHFVPG--------SIEEWLQLLRLEEYIQPLLEQNYKTVRDVTQVTWEDLEDIGI 369
               .:.:..|....|        .:..||:.:.||.|.:.|:...:..:..::.:|.||||:.|:
Human  1246 ---DLAEEAPCLQGGRASGLGEAGMSAWLRAIGLERYEEGLVHNGWDDLEFLSDITEEDLEEAGV 1307

  Fly   370 VKLGHQKKIL 379
            ....|::.:|
Human  1308 QDPAHKRLLL 1317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ckn	NP_611009.1	SAM_caskin1,2_repeat1	254..319	CDD:188896	9/65 (14%)
		SAM	260..316	CDD:197735	9/56 (16%)
		SAM_caskin1,2_repeat2	320..390	CDD:188897	15/67 (22%)
		SAM	326..387	CDD:197735	14/61 (23%)
		Caskin-tail	<887..912	CDD:293238
INPPL1	XP_024304269.1	SH2_SHIP	17..119	CDD:198206
		EEP	446..793	CDD:321002
		Atrophin-1	<965..1280	CDD:331285	71/361 (20%)
		SAM_Ship2	1260..1322	CDD:188890	13/57 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4384
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810