DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ckn and Ostf1

DIOPT Version :9

Sequence 1:	NP_611009.1	Gene:	ckn / 36673	FlyBaseID:	FBgn0033987	Length:	924	Species:	Drosophila melanogaster
Sequence 2:	NP_683690.2	Gene:	Ostf1 / 259275	RGDID:	628849	Length:	214	Species:	Rattus norvegicus

Alignment Length:	186	Identity:	41/186 - (22%)
Similarity:	61/186 - (32%)	Gaps:	62/186 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   417 IPSTPSYVPTTRVSWDDTKIYATSSVLNSTAPSGS-----SCLNSSL-ANG-DAYYCTGSNHECC 474
            |||  :||.....|.|:.        |:..|..|:     .||::.: .|| |....|.....|.
  Rat    61 IPS--NYVAEQAESIDNP--------LHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACH 115

  Fly   475 SGN-DVVLIKVRQPRGKSLESLEDIHDNSTRSHLTFSHYTTTDYGHFGPPTTAAAAAA------- 531
            .|: |:|.:...|| ...|.....:.|                        ||..|||
  Rat   116 GGHKDIVEVLFTQP-NVELNQQNKLGD------------------------TALHAAAWKGYADI 155

  Fly   532 ----MAAAATLQQQHHHQQLLHQQQQQAAAARLLGNNAPGIGWRRSYDDGDITPTN 583
                :|..|....:::.::|.......||.|.||.        ::...||..|.:|
  Rat   156 VQLLLAKGARTDLRNNEKKLALDMATNAACASLLK--------KKQATDGARTLSN 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ckn	NP_611009.1	SAM_caskin1,2_repeat1	254..319	CDD:188896
		SAM	260..316	CDD:197735
		SAM_caskin1,2_repeat2	320..390	CDD:188897
		SAM	326..387	CDD:197735
		Caskin-tail	<887..912	CDD:293238
Ostf1	NP_683690.2	SH3_OSTF1	16..68	CDD:212706	5/8 (63%)
		ANK 1	72..101		7/36 (19%)
		ANK	75..189	CDD:238125	28/146 (19%)
		ANK repeat	76..103	CDD:293786	7/34 (21%)
		Ank_2	77..170	CDD:289560	24/117 (21%)
		ANK repeat	105..137	CDD:293786	8/32 (25%)
		ANK 2	105..135		8/30 (27%)
		ANK repeat	139..170	CDD:293786	8/54 (15%)
		ANK 3	139..168		8/52 (15%)
		ANK repeat	172..206	CDD:293786	10/40 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349396
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24155
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030