Protein Alignment ckn and LOC100334642

DIOPT Version :10

• Sequence 1: NP_611009.1
• Gene: ckn / 36673
• FlyBaseID: FBgn0033987
• Length: 924
• Species: Drosophila melanogaster
• Sequence 2: XP_073801311.1
• Gene: LOC100334642 / 100334642
• -ID: -
• Length: 1285
• Species: Danio rerio
• Alignment Length: 1085
• Identity: 235/1085 - (21%)
• Similarity: 370/1085 - (34%)
• Gaps: 370/1085 - (34%)

  Fly    43 HHQHPNHH-----HPHHQPSIPL---------YRLSGPLRH----HQNH-QADDGISMSGSSIVS 88
            |...|:|.     .|...||:.|         |.|..|..|    |.|. .::.|...|..|...
Zfish   356 HASLPSHRQQLFSRPALSPSLSLSGAPQTDDSYTLYTPNPHLLLPHANALSSNTGAPPSSLSQHF 420

  Fly    89 SPSLEEGGFNLPRETSVALRLKDEVGGTSTAAPTTGGPGGGGATVVGAPPPGAGKPGVAMVPPPP 153
            :||:|:...   ...|.|...::.||.|.:.. :|...|.|.:|...:.|.||.......:|.
Zfish   421 TPSMEDVWV---LRNSCAAGDRNSVGSTGSVG-STRSAGSGQSTESNSVPSGAQPHQHPTIPD-- 479

  Fly   154 VFCATLREPLTHKAAVYYHQQLALQEDQGIDLTQSPGRDSPGSSSGSAGSGSRHSTASLDSGRAS 218
                      .:|||           ...:||.|......|.:.:|:.
Zfish   480 ----------ANKAA-----------PAAVDLLQPDTNKHPDAPTGAP----------------- 506

  Fly   219 SYLTGVSSSGASIRAPLSSPRCSSVSSCSIGSVDRQ-----RNDELIIDWLLEMKHEEYAQLFIA 278
                         |.|:...:.:.....|...|..|     ::.|.|..||.|.:.|:|...|:.
Zfish   507 -------------RRPVLPTQRAGEQGFSQQFVRPQQLLEGKDAEAIYQWLSEFQLEQYTVNFLN 558

  Fly   279 AGYDLPTIARMTPEDLTAIGIKNPHHRERIKQRIDKLQVLDNLPHFVPGSIEEWLQLLRLEEYIQ 343
            ||||:|||:|||||||||||:..|.||::|...|..|.:.|.||.::|..:.|||..:.|.:|.:
Zfish   559 AGYDVPTISRMTPEDLTAIGVTKPGHRKKISLEIGNLSIPDWLPEYIPQDLGEWLSAIGLPQYHK 623

  Fly   344 PLLEQNYKTVRDVTQVTWEDLEDIGIVKLGHQKKILLAIKRVKDIISGKWNPGGANAYQQQE--- 405
            .|.|..|.::..|..:|||||::|||.|||||||::||:|::.||         ..|..|.|
Zfish   624 KLSENGYDSINIVRDLTWEDLQEIGITKLGHQKKLMLAVKKLCDI---------HKALLQTESGQ 679

  Fly   406 --YQRK------------PWQ-FNVPIPSTPSYVPTTRVSWDDTKIYATSSVLNSTAPSGSSCLN 455
              .:||            |.: .::|.|.||.     .:::.|:::              |:.|.
Zfish   680 GTLRRKTPAALDLVAIEPPSESCDLPSPHTPK-----MMTFQDSEL--------------STELQ 725

  Fly   456 SSLANGDAYYCTGSNHECCSGNDVVLIKVRQPRGKSLESLEDIHDNSTRSHLTFSHYTTTDYGHF 520
            |:::         |.:..|  .|.:.||.......|.||::.....|.||.
Zfish   726 SAMS---------SQYSGC--QDGLAIKSAVGMSSSQESIDTRSRGSGRSQ-------------- 765

  Fly   521 GPPTTAAAAAAMAAAA-------------------------------------TLQQQHHHQQLL 548
            .||:|.::.:|..:.:                                     |:..:.:.|.|.
Zfish   766 EPPSTPSSTSAPYSCSRESLTSPDSSPAKERNIPEGRDQGPRPQQLPFSFKYPTITAKPNLQVLN 830

  Fly   549 HQQQQQAAAARLLGNNAPGIGWRRSYDDGDITPTNDATRELLYEQEGGGTLPRQQRGILQRAVLN 613
            :.:.|.::|.  |..::|.:..:|         |...:|..|.:.|     |..:..|....:.|
Zfish   831 YHRAQYSSAT--LDRHSPSVSKKR---------TQSLSRYALSDGE-----PDDEDDIEGAQLAN 879

  Fly   614 -TMPPLEHHHYMNAAAAAEYGAASGVEG------GANYMGGSPLTGKKIAPEPPRRHCSIRNSRT 671
             |||     .|...:.....|..:.::.      |.::........|...|.||:|..|:.:|.|
Zfish   880 VTMP-----SYATLSRKPTRGQLARLQSAPEQSVGRSHSFAIRARRKGPPPPPPKRLSSVSSSST 939

  Fly   672 ---LSGEGVPSGAAAQAHQQAAQQQQGQHMFYGHTAQHWQQQQQQAGAGTGQQPIYANYATIQQT 733
               ...|..|||.........:.....:.:....||:..|:....|..|:.::|       :.::
Zfish   940 SVETVSESPPSGGVENCKSVKSIAAALETVLPVPTAELLQETSTSASEGSKRRP-------LSES 997

  Fly   734 TAEIHCEKYHDSKSTSSID-----------------SIDTIPFANENTGTIKQRLLNRQELQGGG 781
            .::...|....:||.|..|                 |.:.||||.|...|||||
Zfish   998 ESKPMSEPERATKSDSEEDDGMKDSELESSSSPQNSSSECIPFAEEGNLTIKQR----------- 1051

  Fly   782 AGNNNVPGGGHPAHLHSSSSSSSSSSTNTIANIAHSFHSLKSSSSLHDATLARSESMGSTASGGS 846
                  |..|.|..:.:|:::........:........:||.|.::......:.:...:..||.|
Zfish  1052 ------PKVGGPLKVETSTTTECPEKAKPVKTSDLPEFNLKESDTVKRRQKPKDKEQPNAVSGES 1110

  Fly   847 A-------LHLRSPTLDMS------NAGGSTAEP---------------ASSPEAAVPTV----- 878
            :       :.||....|:|      .|....|.|               ||.|..|.|||
Zfish  1111 SDVGSQDTMKLRISESDVSLPYVELPAKPVKAPPPLAPKPPSPLSLSRHASQPAPAHPTVVGSSV 1175

  Fly   879 ------AINNGVPP--------------------------------------------------- 886
                  ::....||
Zfish  1176 TLSVVQSVAFAAPPSPIPYCPSAENTTQGVTSGNVQTPTEGGQGSTLKHQRLEKTSSTLEEALKA 1240

  Fly   887 -------------------KVSVNVLNDIGNMLANLTDELDAMLE 912
                               |.:.|:|:|||||..:|.|:|||||:
Zfish  1241 VERKLTLENNNNVGVSHAVKSAGNILDDIGNMFDDLADQLDAMLD 1285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ckn	NP_611009.1	SAM_caskin1,2_repeat1	254..319	CDD:188896	33/69 (48%)
		SAM_caskin1,2_repeat2	320..390	CDD:188897	32/69 (46%)
		Caskin-tail	<887..912	CDD:465209	14/24 (58%)
LOC100334642	XP_073801311.1	None