DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10257 and FAIM

DIOPT Version :9

Sequence 1:	NP_611008.2	Gene:	CG10257 / 36671	FlyBaseID:	FBgn0033985	Length:	228	Species:	Drosophila melanogaster
Sequence 2:	XP_011511252.1	Gene:	FAIM / 55179	HGNCID:	18703	Length:	233	Species:	Homo sapiens

Alignment Length:	213	Identity:	75/213 - (35%)
Similarity:	125/213 - (58%)	Gaps:	12/213 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SPTLRL-----ENLSTQPTMTQDHVPEDQRYNKQNIVAQWCVPINGKMYRIELEHGTTSGRRMIW 64
            |.||||     .:....|....|..|........::||.|.|.::..:::||.|||||||:|:::
Human    23 SATLRLFLPTMASGDDSPIFEDDESPPYSLEKMTDLVAVWDVALSDGVHKIEFEHGTTSGKRVVY 87

  Fly    65 VNGREVLRRDWMFKLVGEDTFHID--QTRCIIRVDPAPGFKYEYSLYIDGKSHDQYTEDMTRQYR 127
            |:|:|.:|::|||||||::||::.  :|:..|.:|...||.|||:|.|:|||..:|.||.::...
Human    88 VDGKEEIRKEWMFKLVGKETFYVGAAKTKATINIDAISGFAYEYTLEINGKSLKKYMEDRSKTTN 152

  Fly   128 LWLYTDDAAADAPQEYRIMLKLDTLSLYVNDELRTEESVFVHGGTDTKFLLQDTEFVLQARSSGN 192
            .|:...|.     :.:||:|:.|.:.::.|.:.......||..||:|.|.:.:.:..::|.|||.
Human   153 TWVLHMDG-----ENFRIVLEKDAMDVWCNGKKLETAGEFVDDGTETHFSIGNHDCYIKAVSSGK 212

  Fly   193 KHDGIVHTLLANGVAVPE 210
            :.:||:|||:.:...:||
Human   213 RKEGIIHTLIVDNREIPE 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10257	NP_611008.2	FAIM1	34..208	CDD:284354	65/175 (37%)
FAIM	XP_011511252.1	FAIM1	57..228	CDD:284354	65/175 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150780
Domainoid	1	1.000	141	1.000	Domainoid score	I4740
eggNOG	1	0.900	-	-		E1_KOG4352
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8018
Inparanoid	1	1.050	141	1.000	Inparanoid score	I4494
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48789
OrthoDB	1	1.010	-	-		D1301275at2759
OrthoFinder	1	1.000	-	-		FOG0003977
OrthoInspector	1	1.000	-	-		oto89598
orthoMCL	1	0.900	-	-		OOG6_107504
Panther	1	1.100	-	-	LDO	PTHR13088
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3445
SonicParanoid	1	1.000	-	-		X2734
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800