DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lap1 and lrrc57

DIOPT Version :9

Sequence 1:NP_001188938.1 Gene:Lap1 / 36670 FlyBaseID:FBgn0033984 Length:849 Species:Drosophila melanogaster
Sequence 2:NP_001002627.1 Gene:lrrc57 / 436900 ZFINID:ZDB-GENE-040718-372 Length:238 Species:Danio rerio


Alignment Length:216 Identity:62/216 - (28%)
Similarity:111/216 - (51%) Gaps:9/216 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly   229 FEANGNLLDTLPSELSN-WRNVEVLSICSNSLEAFPFSVGMLKSLVTFKCESNGLTELPDSISYL 292
            |:..|..|...|.:|.. ..|:..:.:.:|.:|..|..:|..:.|.:|....|.||.||:.|..|
Zfish    19 FQLTGKGLTEFPEDLQKL
TANLRTVDLSNNKIEELPAFIGSFQHLKSFTISCNKLTSLPNDIGKL 83

  Fly   293 EQLEELVLSHNKLIRLPSTIGMLRSLRFLFADDNQLRQLPDELCSCQQLSVLSVANNQLSALPQN 357
            ::||.|:|:.|:|.:|||:||.|:|||.|....||.::.|..|.:.:||.||.::.||:..:|..
Zfish    84 KKLETLILNGNQLKQLPSSIGQLKSLRTLSLSGNQFKEFPSGLGTLRQLDVLDLSKNQIRVVPAE 148

  Fly   358 IGNLSKMKVLNVVNNYINALPVSMLNLVNLTSMWLSDNQSQ-PLVPLQYLDASTKTQLTCFMLPQ 421
            :..|..::: |:..|.|:::...:.....|..:.|.:|..: ..:||..|   |.:|::...:..
Zfish   149 VAELQAIEI-NLNQNQISSVTQEVSRTPRLKVLRLEENCLELSSIPLSIL---TDSQVSLLSVEG 209

  Fly   422 VTF---KMNSIQAQQQAQEQY 439
            ..|   ||..::...:..|::
Zfish   210 NLFEVKKMRDLEGYDKYMERF 230

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Lap1NP_001188938.1 LRR_RI <21..200 CDD:238064
leucine-rich repeat 21..41 CDD:275380
LRR_8 40..98 CDD:290566
leucine-rich repeat 42..64 CDD:275380
leucine-rich repeat 65..87 CDD:275380
LRR_8 86..140 CDD:290566
leucine-rich repeat 88..110 CDD:275380
leucine-rich repeat 111..133 CDD:275380
leucine-rich repeat 134..156 CDD:275380
LRR_8 156..213 CDD:290566
leucine-rich repeat 157..179 CDD:275380
leucine-rich repeat 180..202 CDD:275380
leucine-rich repeat 203..225 CDD:275380
leucine-rich repeat 226..248 CDD:275380 5/19 (26%)
leucine-rich repeat 272..294 CDD:275380 9/21 (43%)
LRR_8 279..328 CDD:290566 24/48 (50%)
leucine-rich repeat 295..317 CDD:275380 12/21 (57%)
leucine-rich repeat 318..340 CDD:275380 7/21 (33%)
LRR_8 340..396 CDD:290566 13/55 (24%)
leucine-rich repeat 364..386 CDD:275380 3/21 (14%)
PDZ_signaling 770..846 CDD:238492
lrrc57NP_001002627.1 LRR 1 10..36 5/16 (31%)
LRR_RI <37..191 CDD:238064 48/154 (31%)
LRR 2 37..62 5/24 (21%)
leucine-rich repeat 40..65 CDD:275380 5/24 (21%)
LRR_8 62..119 CDD:290566 26/56 (46%)
LRR 3 64..82 7/17 (41%)
leucine-rich repeat 66..85 CDD:275380 8/18 (44%)
LRR 4 83..106 12/22 (55%)
leucine-rich repeat 86..108 CDD:275380 12/21 (57%)
LRR 5 108..128 8/19 (42%)
leucine-rich repeat 109..131 CDD:275380 7/21 (33%)
LRR 6 129..152 7/22 (32%)
leucine-rich repeat 132..154 CDD:275380 7/21 (33%)
LRR 7 154..173 3/19 (16%)
leucine-rich repeat 155..176 CDD:275380 3/21 (14%)
LRR 8 174..199 6/27 (22%)
leucine-rich repeat 177..198 CDD:275380 6/23 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.910

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