Protein Alignment ADPS and D2hgdh

DIOPT Version :9

• Sequence 1: NP_001188935.1
• Gene: ADPS / 36669
• FlyBaseID: FBgn0033983
• Length: 631
• Species: Drosophila melanogaster
• Sequence 2: XP_006245582.1
• Gene: D2hgdh / 301624
• RGDID: 1307976
• Length: 553
• Species: Rattus norvegicus
• Alignment Length: 614
• Identity: 136/614 - (22%)
• Similarity: 224/614 - (36%)
• Gaps: 128/614 - (20%)

  Fly    29 RLSKRVESVIPKKRHEALKWFGWGYNDSQFYGKDGIICFRGEKYPLGGCELPSFTKWVEKKFDLR 93
            |.|.|.:....::....|||.|               |.|....|| .|...|           :
  Rat    33 RASPRWKKTYSQRASAQLKWLG---------------CPRSVYSPL-ACRAYS-----------K 70

  Fly    94 VDTTKQYPQLPRTYPRPVENAPFLHELKGTTQVDYSAEGIDRLVRC--HGQTLNDIYSL------ 150
            |..:.:....|..|  ||:..||    ...::.|.:|      ..|  .|:.:.|...|
  Rat    71 VSGSPEVMLTPERY--PVQRLPF----STVSEEDLAA------FECIIPGRVITDPEQLQTCNVD 123

  Fly   151 WHHKFRRIPDLVVWPRCHDEVVQLVRLANKHNVMLVPFGGGTSVSGAITCPQNESRMICALDTSQ 215
            |....|....:::.|:..:||.|::|...|.|:.:.|.||.|.:.|......:|    ..|.|:.
  Rat   124 WLRTVRGCSKVLLRPQTSEEVSQILRHCYKRNLAVNPQGGNTGMVGGSVPVFDE----VILSTAL 184

  Fly   216 MNRLL-WLNRENLTVCFESGIVGQDLERVLRSEGLTVGHEPDSYEFSTLGGWVATRASGMKKNVY 279
            ||::: :.:...:.|| ::|.|.::|.|.::.....:..:..:.....:||.|||.|.|::...|
  Rat   185 MNQVISFHDVSGILVC-QAGCVLEELSRYVQERDFIMPLDLGAKGSCHIGGNVATNAGGLRFLRY 248

  Fly   280 GNIEDLVVRVRMVTPSGTLEREC--SAPRVSCGPDFNHVILGSEGTLGVITEVVLKVRPLPSLRR 342
            |::...|:.:.:|...||: ..|  |..:.:.|.|...:.:||||||||||.|.:...|.|....
  Rat   249 GSLRGTVLGLEVVLADGTI-LNCLTSLRKDNTGYDLKQMFIGSEGTLGVITAVSIVCPPRPKAVN 312

  Fly   343 YGSLAFPNFEQGVLFMREVAR--RRCQPASVRLMDNEQFMFGQALKPEKSWWASVVDAMKQRYVT 405
            ...|..|.|       .||.:  |.|:.....::...:||..:.:
  Rat   313 VAFLGCPGF-------TEVLQTFRTCKGQLGEILSAFEFMDAECM-------------------- 350

  Fly   406 SWKGIDLNQICAATLLFEGDLKDVQRQEALIYEIAEKFQGFPAGGQNGERGYILTFVIAYIRDFG 470
                    |:....|.....:     ||:..|.:.|     .:|...|.....||.|:..:
  Rat   351 --------QLVGQHLHLTNPV-----QESPFYVLVE-----TSGSSAGHDAEKLTNVLEQV---- 393

  Fly   471 LHQGIVAESFETSVPWDRCSLLCRSVKQRVVSECSKRSINY-YTISCRVTQTYDAGACIYFYFGF 534
            |:.|:|.:.  |.....|...:..::::|:....|:....: |.:|..|.:.||....:....|.
  Rat   394 LNSGLVIDG--TMATDQRKVQMLWALRERITEALSRDGYVFKYDLSLPVERLYDLVIDLRTRLGP 456

  Fly   535 RSTDV------------------ADPVELFEAIEHSARDEILSCGGSLSHHHGVGKIRSHWYRNA 581
            |:..|                  |...||..|:|...........||:|..||:|..:.:....:
  Rat   457 RAKHVVGYGHLGDGNLHLNVTAEAFSQELLGALEPYVYAWTAEQRGSVSAEHGLGFKKKNVLGYS 521

  Fly   582 VTETGSSLYSAAKRHLDPKNIFALGNLLP 610
            .......|....|..||||.|......||
  Rat   522 KPPVAVKLMQQLKAMLDPKGILNPYKTLP 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ADPS	NP_001188935.1	GlcD	152..612	CDD:223354	109/483 (23%)
		FAD_binding_4	159..300	CDD:279851	36/141 (26%)
		FAD-oxidase_C	337..608	CDD:280983	54/291 (19%)
D2hgdh	XP_006245582.1	GlcD	108..550	CDD:223354	111/498 (22%)
		FAD_binding_4	133..270	CDD:279851	36/142 (25%)
		FAD-oxidase_C	307..547	CDD:280983	54/290 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810