Protein Alignment ADPS and LDHD

DIOPT Version :9

• Sequence 1: NP_001188935.1
• Gene: ADPS / 36669
• FlyBaseID: FBgn0033983
• Length: 631
• Species: Drosophila melanogaster
• Sequence 2: XP_024305942.1
• Gene: LDHD / 197257
• HGNCID: 19708
• Length: 567
• Species: Homo sapiens
• Alignment Length: 503
• Identity: 108/503 - (21%)
• Similarity: 169/503 - (33%)
• Gaps: 144/503 - (28%)

  Fly   195 SGAITCPQNESRMICALDTSQMNRLLWLNRENLTVCFESGIVGQDLERVLRSEGLTVGHEPDSYE 259
            ||..|||....  :| ::.:.|:|:|.||:|:.:|..|.|:..:.|...||..||....:|.:
Human   121 SGLSTCPNQGG--VC-VNLTHMDRILELNQEDFSVVVEPGVTRKALNAHLRDSGLWFPVDPGA-- 180

  Fly   260 FSTLGGWVATRASGMKKNVYGNIEDLVVRVRMVTPSGTLERECS--------------------A 304
            .::|.|..||.|||.....||.:.|.|:.:.:|.|.|.|.....                    :
Human   181 DASLCGMAATGASGTNAVRYGTMRDNVLNLEVVLPDGRLLHTAGRGRHFRFGFWPEIPHHTAWYS 245

  Fly   305 PRVS-------CGPDFNHVILGSEGTLGVITEVVLKVRPLPSLRRYGSLAFPNFEQGVLFMREVA 362
            |.||       .|.:...:.:|||||||:||...|::.|.|......:.|||:.:..|.....:.
Human   246 PCVSLGRRKSAAGYNLTGLFVGSEGTLGLITATTLRLHPAPEATVAATCAFPSVQAAVDSTVHIL 310

  Fly   363 RRRCQPASVRLMDNEQFMFGQALKPEKSWWASVVDAMKQRYVTSWKGIDLNQICAATLL--FEGD 425
            :.....|.:..:|.                 .::||. .||      ..||.:.|.||.  |.|.
Human   311 QAAVPVARIEFLDE-----------------VMMDAC-NRY------SKLNCLVAPTLFLEFHGS 351

  Fly   426 LKDVQRQEALIYEIAEKFQGFPAGGQNG-----------ERGYILTF-VIAYIRDFGLHQGIVAE 478
            .:.::.|.....||.:         |||           ||..:.|. ..|:........|....
Human   352 QQALEEQLQRTEEIVQ---------QNGASDFSWAKEAEERSRLWTARHNAWYAALATRPGCKGY 407

  Fly   479 SFETSVPWDRCSLLCRSVKQR----------------------------------------VVSE 503
            |.:..||..|...:....|:.                                        |:|.
Human   408 STDVCVPISRLPEIVVQTKEDLNASGLTGSAHPAAGERWGGVRADQSLGQQEARGGLGWRIVLSS 472

  Fly   504 CSKRSI-------NYYTISCRVTQTYDAGACIYFYFGFRSTDVADPVELFEAIEHSARDEILSCG 561
            ....||       |::              ||...    :.|.|:.:...:|.........|:..
Human   473 GPPGSIVGHVGDGNFH--------------CILLV----NPDDAEELGRVKAFAEQLGRRALALH 519

  Fly   562 GSLSHHHGVGKIRSHWYRNAVTETGSSLYSAAKRHLDPKNIFALGNLL 609
            |:.:..||:|..:....:..|...|.......|..|||:.:...|.:|
Human   520 GTCTGEHGIGMGKRQLLQEEVGAVGVETMRQLKAVLDPQGLMNPGKVL 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ADPS	NP_001188935.1	GlcD	152..612	CDD:223354	108/503 (21%)
		FAD_binding_4	159..300	CDD:279851	36/104 (35%)
		FAD-oxidase_C	337..608	CDD:280983	56/331 (17%)
LDHD	XP_024305942.1	FAD-oxidase_C	<125..567	CDD:332893	105/497 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D824020at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820