DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp317a1 and CYP721A1

DIOPT Version :9

Sequence 1:	NP_001286435.1	Gene:	Cyp317a1 / 36667	FlyBaseID:	FBgn0033982	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	NP_177649.1	Gene:	CYP721A1 / 843850	AraportID:	AT1G75130	Length:	505	Species:	Arabidopsis thaliana

Alignment Length:	486	Identity:	126/486 - (25%)
Similarity:	198/486 - (40%)	Gaps:	114/486 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 AEHY---SAIYKK----FKGSGPFCGFYALLQPRALILDRELIRQIMIKDFWNFNDRGLYCNQKS 119
            |.||   |.:|.|    :.||.|   ..|...||       |||:.:       ...|.:.....
plant    79 APHYHEWSRVYGKTFLYWFGSKP---VVATSDPR-------LIREAL-------TTGGSFDRIGH 126

  Fly   120 DPLSGDLYA-----LRGESWKEMR---------QKLD---PSLEGDRMSLL--YDCLYEEAEQLL 165
            :|||..|||     |||:.|...|         :||.   |.:....|.|:  ::.:....|::.
plant   127 NPLSKLLYAQGLPGLRGDQWAFHRRIAKQAFTMEKLKRWVPQMVTSTMMLMEKWEDMRNGGEEIE 191

  Fly   166 LTVNSTLMSQPHSTVHIQKIMRRYVLSSLAKCVFGLNAEQRK-TYPLEDFEQMTELALNSHKHGY 229
            |.|:              |.|.......|::..||.:.|:.| .:.|:  |:|..|.       |
plant   192 LEVH--------------KEMHNLSAEMLSRTAFGNSVEEGKGIFELQ--ERMMRLF-------Y 233

  Fly   230 LMNLMMIRFPNFCRMLRMR------RTPKQAEEYFIKLLTSIVEQRETSGKPQKDYLQLLIDVKA 288
            |:. ..:..|.| |....:      |..||.....:||    :|..:|:.:.....||..:..
plant   234 LVR-WSVYIPGF-RFFPSKTNREIWRIEKQIRVSILKL----IENNKTAVEKSGTLLQAFMSP-- 290

  Fly   289 LEFITHQYEADKELGAHLQNELAAHAVVFLKAGYEQTANTLSYVLYELALHPELQVRVREEVKKA 353
               .|:|...:::||.   .|:......|..|..|.|||.:::||..||::.|.|...|||| ..
plant   291 ---YTNQNGQEEKLGI---EEVTDECKTFYFAAKETTANLMTFVLVLLAMNQEWQNIAREEV-IC 348

  Fly   354 IERHDGHITHEGIKSLSFMGQVINETLRMHPITPYILRRT-----LNDYAVPDHPKYILVKELFL 413
            :....|..|.:.::.|..:..:||||||::|....:.|.|     |.|..:|      ...:|:|
plant   349 VLGQTGLPTLDILQDLKTLSMIINETLRLYPPAMTLNRDTLKRAKLGDLDIP------AGTQLYL 407

  Fly   414 IIPTHAIHHDPDIY-PDPEEFKPDRWSGPRDSLQEQGTWFGFGVGARSCIGIQFAQLQLRLALAL 477
            .:.  |:|||.:.: .|.|||.|.|:..|:   ::......||:|.|:|:|...|..:.:..||.
plant   408 SVV--AMHHDKETWGDDAEEFNPRRFEDPK---KQSALLVPFGLGPRTCVGQNLAVNEAKTVLAT 467

  Fly   478 LLSEYEFSLN---TRKPLINLEDGIALTLMP 505
            :|..|.|.|:   ...|:      :.:||.|
plant   468 ILKYYSFRLSPSYAHAPV------LFVTLQP 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp317a1	NP_001286435.1	p450	39..466	CDD:299894	115/442 (26%)
CYP721A1	NP_177649.1	p450	26..495	CDD:386267	126/486 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000