DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp317a1 and CYP711A1

DIOPT Version :9

Sequence 1:	NP_001286435.1	Gene:	Cyp317a1 / 36667	FlyBaseID:	FBgn0033982	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	NP_565617.2	Gene:	CYP711A1 / 817157	AraportID:	AT2G26170	Length:	522	Species:	Arabidopsis thaliana

Alignment Length:	544	Identity:	126/544 - (23%)
Similarity:	234/544 - (43%)	Gaps:	103/544 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 IIGLLVLGLLVLLIIAARYQRDYWRYLDIPHERPKKLWPIIRQIMTQTLSTEAMKAEH----YSA 67
            :|..|....:|::|.   ..|..|...::|  .|..: |::..:        .:.|::    :|.
plant    21 LIAFLTFAAVVIVIY---LYRPSWSVCNVP--GPTAM-PLVGHL--------PLMAKYGPDVFSV 71

  Fly    68 IYKKFKGSGPFCGFYALLQPRALILDRELIRQIMIKDFWNFNDRGLYCNQKSDPL-SGDLYALRG 131
            :.|::   ||...|....||..:|.:.||.|::.||.|.:..:|.:.....:.|| ...|:..|.
plant    72 LAKQY---GPIFRFQMGRQPLIIIAEAELCREVGIKKFKDLPNRSIPSPISASPLHKKGLFFTRD 133

  Fly   132 ESWKEMRQKLDPSLEGDRMSLLYDCLYEEAE--QLLLTVNSTLMSQPHSTVHIQKIMRRYVLSSL 194
            :.|.:||..:        :|     ||:.:.  .|:.|::|.:.|..|   ::....|..|.|:|
plant   134 KRWSKMRNTI--------LS-----LYQPSHLTSLIPTMHSFITSATH---NLDSKPRDIVFSNL 182

  Fly   195 ---------AKCVFGLNAEQRKTYPLEDFEQMTELALNSHKH-----------------GYLMNL 233
                     .:..||::.......|::|.| :|:. :|.|.:                 |.|:.:
plant   183 FLKLTTDIIGQAAFGVDFGLSGKKPIKDVE-VTDF-INQHVYSTTQLKMDLSGSLSIILGLLIPI 245

  Fly   234 MMIRFPNFCRML------RMRRTPKQAEEYFIKLLTSIVEQRETSGKPQKDYLQLLI-----DVK 287
            :...|....:.:      |:.:|..:......::::...::.||.   .||:|.|::     |..
plant   246 LQEPFRQVLKRIPGTMDWRVEKTNARLSGQLNEIVSKRAKEAETD---SKDFLSLILKARESDPF 307

  Fly   288 ALEFITHQYEADKELGAHLQNELAAHAVVFLKAGYEQTANTLSYVLYELALHPELQVRVREEVKK 352
            |....|..|             ::|.....|.||...||.|||.|||.::.|.:::.|:.:|:..
plant   308 AKNIFTSDY-------------ISAVTYEHLLAGSATTAFTLSSVLYLVSGHLDVEKRLLQEIDG 359

  Fly   353 AIERHDGHITHEGIKSLSFMGQVINETLRMHPITPYILRRTLNDYAVPDHPKYILVKELFLIIPT 417
            ...|......|:......::.|||.|.:|.:.::|.:.|.|..:..:..   |:|.|..::.:..
plant   360 FGNRDLIPTAHDLQHKFPYLDQVIKEAMRFYMVSPLVARETAKEVEIGG---YLLPKGTWVWLAL 421

  Fly   418 HAIHHDPDIYPDPEEFKPDRW--SGPRDSLQEQGTWFGFGVGARSCIGIQFAQLQLRLALALLLS 480
            ..:..||..:|:||:|||:|:  :|..:..:....:..||:|.|:|:|.:||..:::|.|..|..
plant   422 GVLAKDPKNFPEPEKFKPERFDPNGEEEKHRHPYAFIPFGIGPRACVGQRFALQEIKLTLLHLYR 486

  Fly   481 EYEF--SLNTRKPLINLEDGIALT 502
            .|.|  ||....|| .|:.||.|:
plant   487 NYIFRHSLEMEIPL-QLDYGIILS 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp317a1	NP_001286435.1	p450	39..466	CDD:299894	104/472 (22%)
CYP711A1	NP_565617.2	cytochrome_P450	75..515	CDD:425388	114/476 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.950