Protein Alignment Cyp317a1 and Cyp3a25

DIOPT Version :9

• Sequence 1: NP_001286435.1
• Gene: Cyp317a1 / 36667
• FlyBaseID: FBgn0033982
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: NP_062766.2
• Gene: Cyp3a25 / 56388
• MGIID: 1930638
• Length: 503
• Species: Mus musculus
• Alignment Length: 517
• Identity: 125/517 - (24%)
• Similarity: 254/517 - (49%)
• Gaps: 57/517 - (11%)

  Fly    10 LLVLGLLVLLIIAARYQRDYWRYLDIPHERPKKLWPIIRQIMTQTLSTEAMKAEHYSAIYK---- 70
            :|::..|||..|...|....::.|.||..:|   .|::..|.           .:|..::|
Mouse    13 VLLVTSLVLFYIYGTYSHGLFKKLGIPGPKP---LPLLGTIF-----------NYYDGMWKFDED 63

  Fly    71 KFKGSGPFCGFYALLQPRALILDRELIRQIMIKDFWN-FNDRGLY----CNQKSDPLSGDLYALR 130
            .:|..|...|||...||...|:|.|:|:.:::|:.:: |.:|..:    ..:|:..:|.|
Mouse    64 CYKKYGKIWGFYEGPQPILAIMDPEIIKIVLVKECYSVFTNRRFFGPVGFMKKAITISED----- 123

  Fly   131 GESWKEMRQKLDPSLEGDRMSLLYDCLYEEAEQLLLTVNSTLMSQPHSTVHIQKIMRRYVLSSLA 195
             |.||.:|..|.|:....::..::..:.:..:  :|..|.....:....:.::.|...|.:..:.
Mouse   124 -EEWKRLRTLLSPTFTSGKLKEMFPIMRQYGD--ILVRNLRREEEKGEPISMKDIFGAYSMDVIT 185

  Fly   196 KCVFGLNAEQRKTYPLEDFEQMTELALNSHKHG-YLMNLMMIRF--PNFCRMLRMRRTPKQAEEY 257
            ...||:|.:.... |.:.|.|..:..|...... :|:::::..|  |.: .||.....|:.:..:
Mouse   186 GTSFGVNVDSLNN-PQDPFVQKAKKILKFKIFDPFLLSIILFPFLTPIY-EMLNFSIFPRDSMNF 248

  Fly   258 FIKLLTSIVEQRETSG-KPQKDYLQLLIDVKALEFITHQYEADKELGAHLQNELAAHAVVFLKAG 321
            |.|.:..:.::|..|. |.:.|:|||:::.:.    :...|:.|.|.   ..|:||.||:|:..|
Mouse   249 FKKFVKRMKKERLASNQKNRVDFLQLMMNTQN----SKGQESQKALS---DLEMAAQAVIFIFGG 306

  Fly   322 YEQTANTLSYVLYELALHPELQVRVREEVKKAIERHDGHITHEGIKSLSFMGQVINETLRMHPIT 386
            |:.|:.::|.::||||.||::|.::::|:.:.:. :...:|::.:..:.::..|:||:||::||.
Mouse   307 YDATSTSISLIMYELATHPDVQKKLQDEIDRTLP-NKAPVTYDALMDMEYLDMVVNESLRLYPIA 370

  Fly   387 PYILRRTLNDYAVPDHPKYILVKELFLIIPTHAIHHDPDIYPDPEEFKPDRWSGPRDSLQEQGTW 451
            ..:.|.:..|..:..   ..:.|...::||.:.:|.:|:.:|:|:||.|:|:|.......:...:
Mouse   371 IRLERVSKKDVEING---VFIPKGTVVMIPIYPLHRNPEYWPEPQEFCPERFSKENKGNIDPYIY 432

  Fly   452 FGFGVGARSCIGIQFAQLQLRLALALLL--------SEYEFSLN-TRKPLINLEDGIALTLM 504
            ..||.|.|:|||::||.:.::||:..:|        .|.:..|. :|:|:...|..|.|.::
Mouse   433 MPFGNGPRNCIGMRFALISIKLAVIGVLQNFTVQPCEETQIPLKISREPIFQPEKPIILKVV 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp317a1	NP_001286435.1	p450	39..466	CDD:299894	104/439 (24%)
Cyp3a25	NP_062766.2	p450	39..493	CDD:278495	117/488 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.820