Protein Alignment Cyp317a1 and cyp3a4.2

DIOPT Version :9

• Sequence 1: NP_001286435.1
• Gene: Cyp317a1 / 36667
• FlyBaseID: FBgn0033982
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: NP_001015786.1
• Gene: cyp3a4.2 / 548503
• XenbaseID: XB-GENE-971750
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 526
• Identity: 140/526 - (26%)
• Similarity: 247/526 - (46%)
• Gaps: 87/526 - (16%)

  Fly    10 LLVLGLLVLLIIAARYQRDYWRYLDIPHERPKKLWPII------RQIMTQTLSTEAMKAEHYSAI 68
            :|:..||||:::...:...|::.:.||...|   .|.|      |:.|.| ..||.
 Frog    13 ILLAALLVLILLYGIWPYGYFKKMGIPGPTP---LPFIGTFLEFRKGMVQ-FDTEC--------- 64

  Fly    69 YKKFKGSGPFCGFYALLQPRALILDRELIRQIMIKD-FWNFNDR---GLYCNQKSDPLSGDLYAL 129
               ||..|...|.|...||...|:|..:|:.|::|: :.||.:|   ||     :.|....:...
 Frog    65 ---FKKYGKMWGTYDGRQPVLAIMDPAIIKTILVKECYTNFTNRRNFGL-----NGPFESAITIA 121

  Fly   130 RGESWKEMRQKLDPSLEGDRMSLLYDCLYEEAEQLLLTVNSTL-MSQPHSTVHIQKIMRRYVLSS 193
            ..|.||.:|..|.|:....::..::..:.:.::.|:..:...: ..:|.:|   :.::..|.:..
 Frog   122 EDEQWKRIRNVLSPTFTSGKLKEMFQIMKDYSDILVKNIQGYVEKDEPCAT---KDVIGAYSMDV 183

  Fly   194 LAKCVFGLNAEQRKTYPLEDFE-QMTELALNSHKHGYL--MNLMMIRFPNFCRM----LRMRRTP 251
            :....|.:|.:.... |.:.|. .|.:|.    |.|.|  :.::::.|| |.|.    |.:...|
 Frog   184 ITSTSFSVNIDSLNK-PSDPFVIHMKKLL----KTGLLSPLLILVVIFP-FLRPILEGLNLNFVP 242

  Fly   252 KQAEEYFIKLLTSIVEQR---ETSGKPQKDYLQLLIDVKALEFITHQYEADKELGAHLQNELAAH 313
            |...|:|:..:||..|:|   :.||:  .|.|||::|.:.    |...:...:..|....|:.|.
 Frog   243 KDFTEFFMNAVTSFREKRKKGDHSGR--VDLLQLMMDSRT----TGGNDLSNKHKALTDAEIMAQ 301

  Fly   314 AVVFLKAGYEQTANTLSYVLYELALHPELQVRVREEVKKAIERHDGHITHEGIKSLSFMGQVINE 378
            :|:|:.||||.|:..|||:.|.||.||::|.|:.||:...:. .....|::.:..:.::..||.|
 Frog   302 SVIFIVAGYETTSTALSYLFYNLATHPDVQQRLHEEIDSFLP-DKASPTYDILMQMEYLDMVIQE 365

  Fly   379 TLRMHPITPYILRRT-----LNDYAVPDHPKYILVKELFLIIPTHAIHHDPDIYPDPEEFKPDRW 438
            |||:.|....:.|.:     :|..::|        |.:..:||.:.:..||:.:|:||||:|:|:
 Frog   366 TLRLFPPAGRLERVSKQNVEINGVSIP--------KGIVTLIPAYVLQRDPEYWPEPEEFRPERF 422

  Fly   439 SGPRDSLQEQGTWFGFGVGARSCIGIQFAQLQLRLALALLLSEY------------EFS----LN 487
            |....:.....|:..||.|.|:|||::||.|.:::|:..||..:            |||    |.
 Frog   423 SKENRATHTPFTFLPFGDGPRNCIGLRFALLSMKVAIVTLLQNFSVRPCAETLIPMEFSTIGFLQ 487

  Fly   488 TRKPLI 493
            .:||::
 Frog   488 PKKPIV 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp317a1	NP_001286435.1	p450	39..466	CDD:299894	120/452 (27%)
cyp3a4.2	NP_001015786.1	p450	39..496	CDD:365848	133/500 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	248	1.000	Inparanoid score	I3174
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.060