Protein Alignment Cyp317a1 and Cyp6a2

DIOPT Version :9

• Sequence 1: NP_001286435.1
• Gene: Cyp317a1 / 36667
• FlyBaseID: FBgn0033982
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Alignment Length: 498
• Identity: 170/498 - (34%)
• Similarity: 284/498 - (57%)
• Gaps: 23/498 - (4%)

  Fly     4 IFLIIGLLVLGLLVLLIIAARYQR--DYWRYLDIPHERPKKLWPIIRQIMTQTLSTEAMKAEHYS 66
            :|::|.||:   .:..::|..|.|  :||....:||:.|..|:    ..|........|....|.
  Fly     1 MFVLIYLLI---AISSLLAYLYHRNFNYWNRRGVPHDAPHPLY----GNMVGFRKNRVMHDFFYD 58

  Fly    67 AIYKKFKGSG-PFCGFYALLQPRALILDRELIRQIMIKDFWNFNDRGLYCNQKSDPLSGDLYALR 130
             .|.|::.|| ||.|||.|.:|.|.|:|.:|.:.|:||||.||.|||.:.|.:.|||:..|:.|.
  Fly    59 -YYNKYRKSGFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDPLTQHLFNLD 122

  Fly   131 GESWKEMRQKLDPSLEGDRMSLLYDCLYEEAEQLLLTVNSTL-MSQPHSTVHIQKIMRRYVLSSL 194
            |:.||:|||:|.|:....:|..::..:.:.:|:.:..:...: .:|..:.:.|:::|.|:....:
  Fly   123 GKKWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQNGAVLEIKELMARFTTDVI 187

  Fly   195 AKCVFGLNAEQRKTYPLEDFEQMTELALNSHKHGYLMNLMMIRFPNFCRMLRMRRTPKQAEEYFI 259
            ..|.||:.....:| |:.||..|.:......:||.|:.:.:..||.....||||..|:...::|:
  Fly   188 GTCAFGIECNTLRT-PVSDFRTMGQKVFTDMRHGKLLTMFVFSFPKLASRLRMRMMPEDVHQFFM 251

  Fly   260 KLLTSIVEQRETSGKPQKDYLQLLIDVKALEFIT---HQYEADKELGAHLQNELAAHAVVFLKAG 321
            :|:...:..||.....:.|::.|||::|....:|   .:.....::|     ||||...||..||
  Fly   252 RLVNDTIALRERENFKRNDFMNLLIELKQKGRVTLDNGEVIEGMDIG-----ELAAQVFVFYVAG 311

  Fly   322 YEQTANTLSYVLYELALHPELQVRVREEVKKAIERHDGHITHEGIKSLSFMGQVINETLRMHPIT 386
            :|.:::|:||.|||||.:.::|.|:|.|::..:|..:|.:|:|.||:::::.|||:||||::.:.
  Fly   312 FETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQEGQLTYESIKAMTYLNQVISETLRLYTLV 376

  Fly   387 PYILRRTLNDYAVPDHPKYILVKELFLIIPTHAIHHDPDIYPDPEEFKPDRWSGPRDSLQEQGTW 451
            |::.|:.||||.||.|.|.::.|...:|||..|.|.|.|:||:||.|.|:|:|..:.:.:|...|
  Fly   377 PHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDEDLYPNPETFDPERFSPEKVAARESVEW 441

  Fly   452 FGFGVGARSCIGIQFAQLQLRLALALLLSEYEFSL--NTRKPL 492
            ..||.|.|:|||::|.|:|.|:.||.::|.:..|:  .|..||
  Fly   442 LPFGDGPRNCIGMRFGQMQARIGLAQIISRFRVSVCDTTEIPL 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp317a1	NP_001286435.1	p450	39..466	CDD:299894	148/431 (34%)
Cyp6a2	NP_523628.1	p450	36..502	CDD:278495	159/460 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471839
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	10	9.900