DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp317a1 and erg5

DIOPT Version :9

Sequence 1:	NP_001286435.1	Gene:	Cyp317a1 / 36667	FlyBaseID:	FBgn0033982	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	NP_593788.2	Gene:	erg5 / 2542469	PomBaseID:	SPAC19A8.04	Length:	543	Species:	Schizosaccharomyces pombe

Alignment Length:	257	Identity:	65/257 - (25%)
Similarity:	125/257 - (48%)	Gaps:	41/257 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   235 MIRFP---NFCRMLRMRRTPKQAEEYFIKLLTSIVEQRETSGKP---QKDYLQLLIDVKALEFIT 293
            ::.||   .|.::....::.|....||:|......:..|....|   .::::..:|:       |
pombe   228 LVNFPIVLPFTKVWYGIQSRKVVMRYFMKAAAESRKNMEAGNAPACMMEEWIHEMIE-------T 285

  Fly   294 HQYEADKELGAH---------LQNELAAHAVVFLKAGYEQTANTLSYVLYELALHPELQVRVREE 349
            .:|:::.:.||.         ...|::...:.||.|..:.|::.::::...||.||::..:||||
pombe   286 RKYKSENKEGAEKPSVLIREFSDEEISLTFLSFLFASQDATSSAMTWLFQLLADHPDVLQKVREE 350

  Fly   350 ---VKKAIERHDGHITHEGIKSLSFMGQVINETLRMHP---ITPYILRRTLNDYAVPDHPKYILV 408
               ::|.  ..|..::.:.::.:::...|:.|.||:.|   :.||.:::     |.|..|.|.:.
pombe   351 QLRIRKG--DIDVPLSLDLMEKMTYTRAVVKECLRLRPPVLMVPYRVKK-----AFPITPDYTVP 408

  Fly   409 KELFLIIPT-HAIHHDPDIYPDPEEFKPDRWSGPRDSLQEQG--TWFGFGVGARSCIGIQFA 467
            |:. ::||| :...||..:||:||.|.||||:  .:.|.||.  .|..||.|...|:|.::|
pombe   409 KDA-MVIPTLYGALHDSKVYPEPETFNPDRWA--PNGLAEQSPKNWMVFGNGPHVCLGQRYA 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp317a1	NP_001286435.1	p450	39..466	CDD:299894	64/254 (25%)
erg5	NP_593788.2	CypX	57..505	CDD:225035	65/257 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	88	1.000	Domainoid score	I2119
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	88	1.000	Inparanoid score	I1773
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
TreeFam	0	0.000	Not matched by this tool.
	3	3.050