Protein Alignment Cyp317a1 and cyp-13A5

DIOPT Version :10

• Sequence 1: NP_611004.1
• Gene: Cyp317a1 / 36667
• FlyBaseID: FBgn0033982
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: NP_496112.1
• Gene: cyp-13A5 / 188356
• WormBaseID: WBGene00011672
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 557
• Identity: 128/557 - (22%)
• Similarity: 232/557 - (41%)
• Gaps: 105/557 - (18%)

  Fly     1 MWIIFLIIGLLVLGLLVLLIIAARYQRDYWRYLDIPHERPKKLWPIIRQIMTQTLSTEAMKAEHY 65
            |.:..||.|...:|||...|    :...:|....:...|....:.:|.:..... :...:|...:
 Worm     1 MSLSILIAGASFIGLLTYYI----WIWSFWIRKGVKGPRGFPFFGVIHEFQDYE-NPGLLKLGEW 60

  Fly    66 SAIYKKFKGSGPFCGFYALLQPRALILDRELIRQIMIKDFWNFNDRGLYCNQKSDPLSGD----- 125
            :..|      ||..|....::...::.:.|.:.::.:|.|.||..|      |::|:.||
 Worm    61 TKEY------GPIYGITEGVEKTLIVSNPEFVHEVFVKQFDNFYGR------KTNPIQGDPNKNK 113

  Fly   126 ---LYALRGESWKEMRQKLDPSLEGDRMSLLYDCLYEEAEQLLLTVNSTLMSQPHSTVHIQKIMR 187
               |.:.:|..||.:|....|:.....:..:...:.|...:|:..::..  |.....|.:....:
 Worm   114 RAHLVSAQGHRWKRLRTLSSPTFSNKNLRKIMSTVEETVVELMRHLDDA--SAKGKAVDLLDYYQ 176

  Fly   188 RYVLSSLAKCVFGLNAEQRKTYPL--------EDFEQMTELALNSHK-HGYLMNLMMIRFPNFCR 243
            .:.|..:.:...|.........|:        :|..::..|...... .|.:.....:|||:...
 Worm   177 EFTLDIIGRIAMGQTESLMFRNPMLPKVKGIFKDGRKLPFLVSGIFPIAGTMFREFFMRFPSIQP 241

  Fly   244 MLRMRRTPKQAEEYFIKLLTSIVEQR--------ETSGKPQKDYLQLLIDVKA-LEFI------- 292
            ...:..|.::|       |...:|||        |.||:|| |::.|.:|.:| ::|.
 Worm   242 AFDIMSTVEKA-------LNKRLEQRAADEKAGIEPSGEPQ-DFIDLFLDARANVDFFEEESALG 298

  Fly   293 ---THQYEADKELGAHLQNELAAHAVVFLKAGYEQTANTLSYVLYELALHPELQVRVREEVKKAI 354
               |...:.||:|   ..:|:.....|||.|||:.||.:|||..|.||.|||:|.:::|||.:
 Worm   299 FAKTEIAKVDKQL---TFDEIIGQLFVFLLAGYDTTALSLSYSSYLLARHPEIQKKLQEEVDR-- 358

  Fly   355 ERHDGHITHEGIKSLSFMGQVINETLRMHPITPYILRRTLNDYAVPDHPKYILVKELFLI----- 414
            |..:..:|.:.|..|.:|..|:.|.|||:|:...:..|.             .:||..::
 Worm   359 ECPNPEVTFDQISKLKYMECVVKEALRMYPLASIVHNRK-------------CMKETNVLGVQIE 410

  Fly   415 ------IPTHAIHHDPDIY-PDPEEFKPDRWSGPRDSLQEQGTWFGFGVGARSCIGIQFAQLQLR 472
                  :.|..:|:||.:: .|..||:|:||....:....:|.:..||:|.|.|||::.|.::.:
 Worm   411 KGTNVQVDTWTLHYDPKVWGEDANEFRPERWESGDELFYAKGGYLPFGMGPRICIGMRLAMMEKK 475

  Fly   473 LALALLLSEYEFSLNTRKPLINLEDGIALTLMPLGVI 509
            :.|..:|.:|.|..:|:            |.:||.::
 Worm   476 MLLTHILKKYTFETSTQ------------TEIPLKLV 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp317a1	NP_611004.1	CYP6-like	74..509	CDD:410679	115/482 (24%)
cyp-13A5	NP_496112.1	CYP3A-like	63..511	CDD:410678	116/490 (24%)