Protein Alignment Cyp317a1 and cyp-25A2

DIOPT Version :9

• Sequence 1: NP_001286435.1
• Gene: Cyp317a1 / 36667
• FlyBaseID: FBgn0033982
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: NP_497776.2
• Gene: cyp-25A2 / 175495
• WormBaseID: WBGene00007964
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 507
• Identity: 121/507 - (23%)
• Similarity: 232/507 - (45%)
• Gaps: 67/507 - (13%)

  Fly     3 IIFLIIGLLVLGLLVLLIIAARYQRDYWRYLDIPHERPKKLWPIIRQIMTQTLSTEAM----KAE 63
            :|...|.:|::..::.::.|.|.|......:.:....|......::||:.:   .|.:    ..:
 Worm     4 LILTSILILLVSFIIYILFARREQFKLREKIGLTGPEPHWFMGNLKQIVDR---KEKLGYDDSNK 65

  Fly    64 HYSAIYKKFKGSGPFCGFYALLQPRALILDRELIRQIMIKDFWNFNDRGL----YCNQKSDPLSG 124
            .::.::|::   |...|.|...|...::.:.|.|:::.||:|.||:||.:    ..||.:..|..
 Worm    66 WFNELHKQY---GETFGIYFGAQMNIVLSNEEDIKEVFIKNFSNFSDRIVPPIFDSNQLNQSLLQ 127

  Fly   125 DLYALRGESWKEMRQKLDPSLEGDRMSLLYDCLYEEAEQLLLTVNSTLMSQPHSTVHIQKIMRRY 189
            :.||   ..||..|..:.|.....:|..:.:.::.:.:..|..:.....|.....::  :..:..
 Worm   128 NTYA---TGWKHTRSAIAPIFSTGKMKAMQETIHSKVDLFLDILREKASSGQKWDIY--EDFQGL 187

  Fly   190 VLSSLAKCVFGLNAEQRKTYPLEDFEQMTELALNSHK--------HGYLMNLMMIRFPNFCRMLR 246
            .|..:.||.|.:::..::       ::.....:|:.|        |..::....| .|....:.|
 Worm   188 TLDVIGKCAFAIDSNCQR-------DRNDVFYVNARKFIANIDIRHSKVIAASFI-LPELAPLWR 244

  Fly   247 --MRRTP-KQAEEYFIKLLTSIVEQRE-TSGKPQKDYLQLLIDVKALEFITHQYEADKELGAHLQ 307
              .:.|| ..||...::.|:::.|:|. ..|....|.|:||::          .|.||......|
 Worm   245 ALYKYTPLADAEIPLVEGLSNVYERRRGGEGSDSVDLLKLLLN----------REDDKSKPMTKQ 299

  Fly   308 NELAAHAVVFLKAGYEQTANTLSYVLYELALHPELQVRVREEVKKAIERHDGHITHEGIKSLSFM 372
             |:..:...||.||||.|:..::|..|.|:.:|.:|.::.||:.:|  :.:|.:|::.|.::.::
 Worm   300 -EVIENCFAFLLAGYETTSTAMTYCSYLLSKYPNVQQKLYEEIMEA--KENGGLTYDSIHNMKYL 361

  Fly   373 GQVINETLRMH-PITPYILRRTLNDYAVPD--HPKYILVKELFLIIPTHAIHHDPDIYPDPEEFK 434
            ..|..||||.: |:..:|.||.|.|..:..  :||..:|..|     .|.:|.:|:.:..||||.
 Worm   362 DYVYKETLRCYPPVIHFINRRCLADITIRGQFYPKGSVVTCL-----PHTVHLNPENWDSPEEFH 421

  Fly   435 PDR---WSGPRDSLQEQGTWFGFGVGARSCIGIQFAQLQLRLALALLLSEYE 483
            |:|   |.....||:    |..||||.|.|:|::||:::.:..:..||..:|
 Worm   422 PERFENWEEKSSSLK----WIPFGVGPRYCVGMRFAEMEFKTTIVKLLDTFE 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp317a1	NP_001286435.1	p450	39..466	CDD:299894	110/452 (24%)
cyp-25A2	NP_497776.2	p450	38..498	CDD:278495	115/473 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	208	1.000	Domainoid score	I1665
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	213	1.000	Inparanoid score	I2346
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.980